NXPH3 抗体 (AA 5-217)
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北京 101111
Quick Overview for NXPH3 抗体 (AA 5-217) (ABIN7601872)
抗原
See all NXPH3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 5-217
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原理
- Anti-NXPH3 Antibody
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产品特性
- Anti-NXPH3 Antibody (ABIN7601872). Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NXPH3 recombinant protein (Position: R5-K217). Human NXPH3 shares 95.8% amino acid (aa) sequence identity with mouse and rat NXPH3, respectively.
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亚型
- IgG
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anti-Neurexophilin 3 (NXPH3) (AA 1-252) antibody
NXPH3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C8 unconjugated
anti-Neurexophilin 3 (NXPH3) (Internal Region) antibodyNXPH3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neurexophilin 3 (NXPH3) (Internal Region) antibodyNXPH3 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neurexophilin 3 (NXPH3) (Internal Region) antibodyNXPH3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neurexophilin 3 (NXPH3) (AA 1-252) antibodyNXPH3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Neurexophilin 3 (NXPH3) (AA 143-192) antibodyNXPH3 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, 兔, Pig, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Neurexophilin 3 (NXPH3) (AA 35-84) antibodyNXPH3 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Neurexophilin 3 (NXPH3) (N-Term) antibodyNXPH3 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry, 2-5 μg/mL, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- NXPH3 (Neurexophilin 3 (NXPH3))
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别名
- NXPH3
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背景
- Neurexophilin-3 is a protein that in humans is encoded by the NXPH3 gene. Neurexophilin-3 (NXPH-3) is a neuropeptide-like secreted glycoprotein in the neurexophilin family. The 252 amino acid (aa) NXPH-3 precursor contains a 22 aa signal peptide, plus a 230 aa proprecursor that is likely cleaved at a basic motif, producing a 76 aa propeptide and a 154 aa mature protein. Mature rat NXPH-3 shares 99 % , 95 % and 92 % aa identity with mouse, human and bovine NXPH-3, respectively. It contains motifs that are conserved among all neurexophilins, including three potential N-glycosylation sites in the N-terminal portion and six cysteines in the C-terminal portion. NXPH-3 is expressed selectively in subplate-derived neurons in the cortex, granule cells in the vestibulocerebellum, and Cajal-Retzius cells during development. NXPH-1 is the neurexophilin most similar to NXPH-3, sharing 69 % aa identity within the mature region. Expression of NXPH-1 and NXPH-3 does not appear to overlap, with NXPH-1 expression occurring mainly by cells that resemble inhibitory interneurons. Both are tightly bound extracellular ligands of alpha -neurexins, synaptic transmembrane molecules that are essential for calcium-triggered neurotransmitter release. Genetic deletion of NXPH-1 and/or NXPH-3 produces no anatomical effect, although mice lacking NXPH-3 show specific defects in motor coordination. Of the other known neurexophilins, NXPH-2 is not expressed in rodents, and NXPH-4 does not bind alpha -neurexins.
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分子量
- 28 kDa
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基因ID
- 11248
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UniProt
- O95157
抗原
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