Neural Wiskott-Aldrich syndrome protein (WASL) (AA 5-211) 抗体
Quick Overview for Neural Wiskott-Aldrich syndrome protein (WASL) (AA 5-211) 抗体 (ABIN7601871)
抗原
See all Neural Wiskott-Aldrich syndrome protein (WASL) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 5-211
-
原理
- Anti-N WASP/WASL Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-N WASP/WASL Antibody Picoband® (ABIN7601871). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human N WASP/WASL recombinant protein (Position: Q5-H211).
-
亚型
- IgG
-
-
anti-Neural Wiskott-Aldrich syndrome protein (WASL) antibody
WASL 适用: 人, 小鼠, 大鼠 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neural Wiskott-Aldrich syndrome protein (WASL) (AA 1-250) antibodyWASL 适用: 人 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neural Wiskott-Aldrich syndrome protein (WASL) (AA 97-184) antibodyWASL 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5F4 unconjugated
anti-Neural Wiskott-Aldrich syndrome protein (WASL) (Middle Region) antibodyWASL 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neural Wiskott-Aldrich syndrome protein (WASL) (AA 165-198), (N-Term) antibodyWASL 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB52982 unconjugated
anti-Neural Wiskott-Aldrich syndrome protein (WASL) (AA 1-505) antibodyWASL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Neural Wiskott-Aldrich syndrome protein (WASL) (AA 182-231) antibodyWASL 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Neural Wiskott-Aldrich syndrome protein (WASL) antibodyWASL 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Cotta-de-Almeida, V., Westerberg, L., Maillard, M. H., Onaldi, D., Wachtel, H., Meelu, P., Chung, U., Xavier, R., Alt, F. W., Snapper, S. B. Wiskott-Aldrich syndrome protein (WASP) and N-WASP are critical for T cell development. Proc. Nat. Acad. Sci. 104: 15424-15429, 2007. 2. Fukuoka, M., Miki, H., Takenawa, T. Identification of N-WASP homologs in human and rat brain. Gene 196: 43-48, 1997. 3. Guenin-Mace, L., Veyron-Churlet, R., Thoulouze, M.-I., Romet-Lemonne, G., Hong, H., Leadlay, P. F., Danckaert, A., Ruf, M.-T., Mostowy, S., Zurzolo, C., Bousso, P., Chretien, F., Carlier, M.-F., Demangel, C. Mycolactone activation of Wiskott-Aldrich syndrome proteins underpins Buruli ulcer formation. J. Clin. Invest. 123: 1501-1512, 2013. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- Neural Wiskott-Aldrich syndrome protein (WASL)
-
别名
- WASL
-
背景
-
Synonyms: POU domain, class 4, transcription factor 1
Tissue Specificity: Expressed in the brain and the retina. Present in the developing brain, spinal cord and eye.
Background: Neural Wiskott-Aldrich syndrome protein is a protein that in humans is encoded by the WASL gene. This gene encodes a member of the Wiskott-Aldrich syndrome (WAS) protein family. Wiskott-Aldrich syndrome proteins share similar domain structure, and associate with a variety of signaling molecules to alter the actin cytoskeleton. The encoded protein is highly expressed in neural tissues, and interacts with several proteins involved in cytoskeletal organization, including cell division control protein 42 (CDC42) and the actin-related protein-2/3 (ARP2/3) complex. The encoded protein may be involved in the formation of long actin microspikes, and in neurite extension.
-
分子量
- 70 kDa
-
基因ID
- 8976
-
UniProt
- O00401
抗原
-
