Peroxiredoxin 2 抗体 (AA 5-127)
Quick Overview for Peroxiredoxin 2 抗体 (AA 5-127) (ABIN7601867)
抗原
See all Peroxiredoxin 2 (PRDX2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 5-127
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原理
- Anti-peroxiredoxin 2/PRDX2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-peroxiredoxin 2/PRDX2 Antibody Picoband® (ABIN7601867). Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human peroxiredoxin 2/PRDX2 recombinant protein (Position: N5-R127).
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亚型
- IgG
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anti-Peroxiredoxin 2 (PRDX2) (AA 1-198) antibody
PRDX2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4E10-2D2 unconjugated
anti-Peroxiredoxin 2 (PRDX2) (AA 6-164) antibodyPRDX2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 2 (PRDX2) (AA 6-164) antibodyPRDX2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 2 (PRDX2) (C-Term) antibodyPRDX2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 2 (PRDX2) (AA 2-65) antibodyPRDX2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 2 (PRDX2) antibodyPRDX2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 2 (PRDX2) (AA 1-142) antibodyPRDX2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 2 (PRDX2) antibodyPRDX2 适用: 人 WB, IP, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 2 (PRDX2) (AA 169-198), (C-Term) antibodyPRDX2 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB20888 unconjugated
anti-Peroxiredoxin 2 (PRDX2) (AA 1-198) antibodyPRDX2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Choi, M. H., Lee, I. K., Kim, G. W., Kim, B. U., Han, Y.-H., Yu, D.-Y., Park, H. S., Kim, K. Y., Lee, J. S., Choi, C., Bae, Y. S., Lee, B. I., Rhee, S. G., Kang, S. W. Regulation of PDGF signalling and vascular remodelling by peroxiredoxin II. Nature 435: 347-353, 2005. 2. Lee, T.-H., Kim, S.-U., Yu, S.-L., Kim, S. H., Park, D. S., Moon, H.-B., Dho, S. H., Kwon, K.-S., Kwon, H. J., Han, Y.-H., Jeong, S., Kang, S. W., Shin, H.-S., Lee, K.-K., Rhee, S. G., Yu, D.-Y. Peroxiredoxin II is essential for sustaining life span of erythrocytes in mice. Blood 101: 5033-5038, 2003. 3. Pahl, P., Berger, R., Hart, I., Chae, H. Z., Rhee, S. G., Patterson, D. Localization of TDPX1, a human homologue of the yeast thioredoxin-dependent peroxide reductase gene (TPX), to chromosome 13q12. Genomics 26: 602-606, 1995. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Peroxiredoxin 2 (PRDX2)
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别名
- PRDX2
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背景
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Synonyms: Neuronal acetylcholine receptor subunit alpha-3, CHRNA3, NACHRA3
Background: PRDX2(peroxiredoxin 2) also known as NKEFB, PRP, PRX2, PRXII or TPX1, is a?protein?that in humans is encoded by the?PRDX2?gene. This gene encodes a member of the peroxiredoxin family of antioxidant?enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides.?The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The?Prdx2?-/- mice were healthy in appearance and fertile. Choi et al.(2005)?demonstrated that?PRDX2?is a negative regulator of PDGF signaling. Prx II deficiency results in increased production of peroxide, enhanced activation of PDGF receptor and phospholipase C-gamma-1, and subsequently increased cell proliferation and migration in response to PDGF. PRX2 accounted for about half of the thioredoxin activity in parasite extracts, and PRX2 expression was increased in the presence of chloroquine, regardless of P. falciparum strain susceptibility to the drug.
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分子量
- 22 kDa
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基因ID
- 7001
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UniProt
- P32119
抗原
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