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AFAP 抗体 (AA 498-730)

This anti-AFAP antibody is a 兔 多克隆 antibody detecting AFAP in WB, ELISA, IHC 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7601861
发货至: 中国

Quick Overview for AFAP 抗体 (AA 498-730) (ABIN7601861)

抗原

See all AFAP (AFAP1) 抗体
AFAP (AFAP1) (Actin Filament Associated Protein 1 (AFAP1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This AFAP antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • 抗原表位

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    AA 498-730

    原理

    Anti-AFAP/AFAP1 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-AFAP/AFAP1 Antibody Picoband® (ABIN7601861). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human AFAP/AFAP1 recombinant protein (Position: A498-T730).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.25 μg/mL,Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Baisden, J. M., Qian, Y., Zot, H. M., Flynn, D. C. The actin filament-associated protein AFAP-110 is an adaptor protein that modulates changes in actin filament integrity. Oncogene 20: 6435-6447, 2001. 2. Flynn, D. C., Leu, T. H., Reynolds, A. B., Parsons, J. T. Identification and sequence analysis of cDNAs encoding a 110-kilodalton actin filament-associated pp60src substrate. Molec. Cell Biol. 13: 7892-7900, 1993. 3. Kanner, S. B., Reynolds, A. B., Wang, H.-C. R., Vines, R. R., Parsons, J. T. The SH2 and SH3 domains of pp60src stable association with tyrosine phosphorylated proteins p130 and p110. EMBO J. 10: 1689-1698, 1991.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    AFAP (AFAP1) (Actin Filament Associated Protein 1 (AFAP1))

    别名

    AFAP1

    背景

    Synonyms: Transcription factor MafA, Pancreatic beta-cell-specific transcriptional activator, RIPE3b1 factor, V-maf musculoaponeurotic fibrosarcoma oncogene homolog A, MAFA

    Tissue Specificity: Preferentially expressed in regulatory T-cells (Tregs).

    Background: Actin filament-associated protein 1 is a protein that in humans is encoded by the AFAP1 gene. The protein encoded by this gene is a Src binding partner. It may represent a potential modulator of actin filament integrity in response to cellular signals, and may function as an adaptor protein by linking Src family members and/or other signaling proteins to actin filaments. Multiple transcript variants encoding different isoforms have been found for this gene.

    分子量

    120 kDa

    基因ID

    60312

    UniProt

    Q8N556
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