Mps1 抗体 (AA 487-821)
Quick Overview for Mps1 抗体 (AA 487-821) (ABIN7601844)
抗原
See all Mps1 (TTK) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 487-821
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原理
- Anti-TTK/Mps1/TTK Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-TTK/Mps1/TTK Antibody Picoband® (ABIN7601844). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TTK/Mps1/TTK recombinant protein (Position: Q487-S821).
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亚型
- IgG
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anti-Mps1 (TTK) (AA 532-786) antibody
TTK 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mps1 (TTK) (AA 1-176) antibodyTTK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G7 unconjugated
anti-Mps1 (TTK) (AA 527-786) antibodyTTK 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mps1 (TTK) (AA 370-492) antibodyTTK 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mps1 (TTK) (Thr676) antibodyTTK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mps1 (TTK) (AA 1-857) antibodyTTK 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Mps1 (TTK) (AA 601-700) antibodyTTK 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mps1 (TTK) (AA 517-856) antibodyTTK 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Mps1 (TTK) (AA 1-176) antibodyTTK 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3G7 unconjugated
anti-Mps1 (TTK) (AA 1-857) antibodyTTK 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Lindberg, R. A., Fischer, W. H., Hunter, T. Characterization of a human protein threonine kinase isolated by screening an expression library with antibodies to phosphotyrosine. Oncogene 8: 351-359, 1993. 2. Mills, G. B., Schmandt, R., McGill, M., Amendola, A., Hill, M., Jacobs, K., May, C., Rodricks, A.-M., Campbell, S., Hogg, D. Expression of TTK, a novel human protein kinase, is associated with cell proliferation. J. Biol. Chem. 267: 16000-16006, 1992. 3. Poss, K. D., Wilson, L. G., Keating, M. T. Heart regeneration in zebrafish. Science 298: 2188-2190, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Mps1 (TTK)
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别名
- TTK
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背景
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Synonyms: Dual specificity protein kinase TTK, Phosphotyrosine picked threonine-protein kinase, PYT, TTK, MPS1, MPS1L1
Tissue Specificity: Present in rapidly proliferating cell lines.
Background: Dual specificity protein kinase TTK is a protein that in humans is encoded by the XRCC2 gene. This gene is mapped to 6q14.1. This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.
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分子量
- 97 kDa
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基因ID
- 7272
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UniProt
- P33981
抗原
-
