FOXM1 抗体 (AA 48-763)
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北京 101111
Quick Overview for FOXM1 抗体 (AA 48-763) (ABIN7601839)
抗原
See all FOXM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 48-763
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原理
- Anti-FOXM1 Antibody
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产品特性
- Anti-FOXM1 Antibody (ABIN7601839). Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human FOXM1 recombinant protein (Position: K48-Q763). Human FOXM1 shares 78.9% and 81.1% amino acid (aa) sequence identity with mouse and rat FOXM1, respectively.
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亚型
- IgG
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anti-Forkhead Box M1 (FOXM1) (AA 702-801) antibody
FOXM1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5G10 unconjugated
anti-Forkhead Box M1 (FOXM1) (Middle Region) antibodyFOXM1 适用: 人, 大鼠, 小鼠, 犬, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box M1 (FOXM1) (AA 209-460) antibodyFOXM1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box M1 (FOXM1) (C-Term) antibodyKO Validated FOXM1 适用: 人 WB, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box M1 (FOXM1) antibodyKO Validated FOXM1 适用: 人 WB, IP, IHC (p), ChIP 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box M1 (FOXM1) (AA 649-748) antibodyFOXM1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 6F11A8 unconjugated
anti-Forkhead Box M1 (FOXM1) (N-Term) antibodyFOXM1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box M1 (FOXM1) (AA 22-110) antibodyFOXM1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2H4 unconjugated
anti-Forkhead Box M1 (FOXM1) (AA 301-400) antibodyFOXM1 适用: 人 ELISA 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box M1 (FOXM1) (AA 22-110) antibodyFOXM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G3 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- FOXM1 (Forkhead Box M1 (FOXM1))
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别名
- FOXM1
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背景
- Forkhead box protein M1, also called FOXM1, is a protein that in humans is encoded by the FOXM1 gene. It is mapped to 12p13.33. The protein encoded by this gene is a member of the FOX family of transcription factors. FOXM1 is known to play a key role in cell cycle progression where endogenous FOXM1 expression peaks at S and G2/M phases and also in the control of cell proliferation. FOXM1 gene is now known as a human proto-oncogene. Abnormal upregulation of FOXM1 is involved in the oncogenesis of basal cell carcinoma, the most common human cancer worldwide. It was hypothesized that FOXM1 induces cancer initiation through stem/progenitor cell expansion. What's more, FOXM1 has been shown to modulate the epigenome. It was found that overexpression of FOXM1 "brain washes" normal cells to adopt cancer-like epigenome.
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分子量
- 110 kDa
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基因ID
- 2305
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UniProt
- Q08050
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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