SULF2 抗体 (AA 471-614)
Quick Overview for SULF2 抗体 (AA 471-614) (ABIN7601821)
抗原
See all SULF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 471-614
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原理
- Anti-SULF2 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-SULF2 Antibody Picoband® (ABIN7601821). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SULF2 recombinant protein (Position: K471-D614).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Dai, Y., Yang, Y., MacLeod, V., Yue, X., Rapraeger, A. C., Shriver, Z., Venkataraman, G., Sasisekharan, R., Sanderson, R. D. HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth in vivo. J. Biol. Chem. 280: 40066-40073, 2005. 2. Morimoto-Tomita, M., Uchimura, K., Werb, Z., Hemmerich, S., Rosen, S. D. Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans. J. Biol. Chem. 277: 49175-49185, 2002. 3. Nagase, T., Ishikawa, K., Kikuno, R., Hirosawa, M., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 6: 337-345, 1999. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SULF2 (Sulfatase 2 (SULF2))
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别名
- SULF2
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背景
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Synonyms: Fructose-bisphosphate aldolase B, Liver-type aldolase, ALDOB, ALDB
Tissue Specificity: Pancreas-specific (at protein level). Loss of expression is seen in ductal type pancreas cancers.
Background: Extracellular sulfatase Sulf-2 is an enzyme that in humans is encoded by the SULF2 gene. Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules
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分子量
- 135 kDa
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基因ID
- 55959
抗原
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