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SULF2 抗体 (AA 471-614)

This anti-SULF2 antibody is a 兔 多克隆 antibody detecting SULF2 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7601821
发货至: 中国

Quick Overview for SULF2 抗体 (AA 471-614) (ABIN7601821)

抗原

See all SULF2 抗体
SULF2 (Sulfatase 2 (SULF2))

适用

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宿主

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克隆类型

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多克隆

标记

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This SULF2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 471-614

    原理

    Anti-SULF2 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-SULF2 Antibody Picoband® (ABIN7601821). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human SULF2 recombinant protein (Position: K471-D614).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Dai, Y., Yang, Y., MacLeod, V., Yue, X., Rapraeger, A. C., Shriver, Z., Venkataraman, G., Sasisekharan, R., Sanderson, R. D. HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth in vivo. J. Biol. Chem. 280: 40066-40073, 2005. 2. Morimoto-Tomita, M., Uchimura, K., Werb, Z., Hemmerich, S., Rosen, S. D. Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans. J. Biol. Chem. 277: 49175-49185, 2002. 3. Nagase, T., Ishikawa, K., Kikuno, R., Hirosawa, M., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 6: 337-345, 1999.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    SULF2 (Sulfatase 2 (SULF2))

    别名

    SULF2

    背景

    Synonyms: Fructose-bisphosphate aldolase B, Liver-type aldolase, ALDOB, ALDB

    Tissue Specificity: Pancreas-specific (at protein level). Loss of expression is seen in ductal type pancreas cancers.

    Background: Extracellular sulfatase Sulf-2 is an enzyme that in humans is encoded by the SULF2 gene. Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules

    分子量

    135 kDa

    基因ID

    55959
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