alpha 2 Antiplasmin 抗体 (AA 461-491)
Quick Overview for alpha 2 Antiplasmin 抗体 (AA 461-491) (ABIN7601808)
抗原
See all alpha 2 Antiplasmin (SERPINF2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 461-491
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原理
- Anti-Alpha 2 Antiplasmin/SERPINF2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Alpha 2 Antiplasmin/SERPINF2 Antibody Picoband® (ABIN7601808). Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Alpha 2 Antiplasmin/SERPINF2 recombinant protein (Position: K461-K491).
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亚型
- IgG
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anti-Alpha2 Antiplasmin (SERPINF2) (Internal Region) antibody
Verified SERPINF2 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Alpha2 Antiplasmin (SERPINF2) (Center) antibodySERPINF2 适用: 人, 小鼠 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Alpha2 Antiplasmin (SERPINF2) (AA 1-491) antibodySERPINF2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Alpha2 Antiplasmin (SERPINF2) (AA 1-491) antibodySERPINF2 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Alpha2 Antiplasmin (SERPINF2) (AA 1-491) antibodySERPINF2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Alpha2 Antiplasmin (SERPINF2) (C-Term) antibodySERPINF2 适用: 人, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Alpha2 Antiplasmin (SERPINF2) (AA 302-491) antibodySERPINF2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Alpha2 Antiplasmin (SERPINF2) (AA 161-260) antibodySERPINF2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Alpha2 Antiplasmin (SERPINF2) (AA 188-453) antibodySERPINF2 适用: 人, 小鼠 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Alpha2 Antiplasmin (SERPINF2) (N-Term) antibodySERPINF2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bangert, K., Johnsen, A. H., Christensen, U., Thorsen, S. Different N-terminal forms of alpha-2-plasmin-inhibitor in human plasma. Biochem. J. 291: 623-625, 1993. 2. Favier, R., Aoki, N., de Moerloose, P. Congenital alpha-2-plasmin inhibitor deficiencies: a review. Brit. J. Haemat. 114: 4-10, 2001. 3. Hirosawa, S., Nakamura, Y., Miura, O., Sumi, Y., Aoki, N. Organization of the human alpha-2-plasmin inhibitor gene. Proc. Nat. Acad. Sci. 85: 6836-6840, 1988. Note: Erratum: Proc. Nat. Acad. Sci. 86: 1612-1613, 1989. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))
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别名
- SERPINF2
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背景
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Synonyms: Low affinity immunoglobulin epsilon Fc receptor, BLAST-2, C-type lectin domain family 4 member J, Fc-epsilon-RII, Immunoglobulin E-binding factor, Lymphocyte IgE receptor, CD23, Low affinity immunoglobulin epsilon Fc receptor membrane-bound form, Low affinity immunoglobulin epsilon Fc receptor soluble form, FCER2, CD23A, CLEC4J, FCE2, IGEBF
Tissue Specificity: Highly expressed on high endothelial venules (HEV) and lamina propia venules found in the small intestine, and to a lesser extent in the colon and spleen. Very low levels of expression found in pancreas and brain. Not expressed in the thymus, prostate, ovaries, testis, heart, placenta, lung, liver, skeletal muscle, kidney or peripheral blood leukocytes.
Background: Alpha 2-antiplasmin (or α2-antiplasmin or plasmin inhibitor) is a serine protease inhibitor (serpin) responsible for inactivating plasmin. Plasmin is an important enzyme that participates in fibrinolysis and degradation of various other proteins. This protein is encoded by the SERPINF2 gene. This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.
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分子量
- 65 kDa
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基因ID
- 5345
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UniProt
- P08697
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途径
- Regulation of Systemic Arterial Blood Pressure by Hormones
抗原
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