SARS2 抗体 (AA 46-518)
Quick Overview for SARS2 抗体 (AA 46-518) (ABIN7601804)
抗原
See all SARS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 46-518
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原理
- Anti-SARS2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SARS2 Antibody Picoband® (ABIN7601804). Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SARS2 recombinant protein (Position: E46-S518).
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亚型
- IgG
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anti-seryl-tRNA Synthetase 2, Mitochondrial (SARS2) (AA 1-518) antibody
SARS2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-seryl-tRNA Synthetase 2, Mitochondrial (SARS2) (AA 1-518) antibodySARS2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-seryl-tRNA Synthetase 2, Mitochondrial (SARS2) (AA 289-518) antibodySARS2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-seryl-tRNA Synthetase 2, Mitochondrial (SARS2) (AA 108-157) antibodySARS2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-seryl-tRNA Synthetase 2, Mitochondrial (SARS2) (AA 315-344) antibodySARS2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB14863 unconjugated
anti-seryl-tRNA Synthetase 2, Mitochondrial (SARS2) (AA 160-188), (N-Term) antibodySARS2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB14927 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Belostotsky, R., Ben-Shalom, E., Rinat, C., Becker-Cohen, R., Feinstein, S., Zeligson, S., Segel, R., Elpeleg, O., Nassar, S., Frishberg, Y. Mutations in the mitochondrial seryl-tRNA synthetase cause hyperuricemia, pulmonary hypertension, renal failure in infancy and alkalosis, HUPRA syndrome. Am. J. Hum. Genet. 88: 193-200, 2011. 2. Bonnefond, L., Fender, A., Rudinger-Thirion, J., Giege, R., Florentz, C., Sissler, M. Toward the full set of human mitochondrial aminoacyl-tRNA synthetases: characterization of AspRS and TyrRS. Biochemistry 44: 4805-4816, 2005. 3. Chimnaronk, S., Gravers Jeppesen, M., Suzuki, T., Nyborg, J., Watanabe, K. Dual-mode recognition of noncanonical tRNAs(Ser) by seryl-tRNA synthetase in mammalian mitochondria. EMBO J. 24: 3369-3379, 2005. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SARS2 (seryl-tRNA Synthetase 2, Mitochondrial (SARS2))
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别名
- SARS2
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背景
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Synonyms: Ubiquitin carboxyl-terminal hydrolase 44, Deubiquitinating enzyme 44, Ubiquitin thioesterase 44, Ubiquitin-specific-processing protease 44, USP44
Tissue Specificity: Expressed in testis. Expressed at high levels in T-cell acute lymphoblastic leukemia.
Background: Seryl-tRNA synthetase, mitochondrial is an enzyme that in humans is encoded by the SARS2 gene. This gene encodes the mitochondrial seryl-tRNA synthethase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA(Ser) and participates in the biosynthesis of selenocysteinyl-tRNA(sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalytic domain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by a biional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are within the critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to this disease. Multiple transcript variants encoding different isoforms have been identified for this gene.
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分子量
- 53 kDa
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基因ID
- 54938
抗原
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