PDIA5 抗体 (AA 46-481)
Quick Overview for PDIA5 抗体 (AA 46-481) (ABIN7601801)
抗原
See all PDIA5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 46-481
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原理
- Anti-PDIA5 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PDIA5 Antibody Picoband® (ABIN7601801). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PDIA5 recombinant protein (Position: R46-Y481).
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亚型
- IgG
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anti-Protein Disulfide Isomerase Associated 5 (PDIA5) (AA 378-506) antibody
PDIA5 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Disulfide Isomerase Associated 5 (PDIA5) (AA 31-130) antibodyPDIA5 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A3 unconjugated
anti-Protein Disulfide Isomerase Associated 5 (PDIA5) antibodyPDIA5 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Disulfide Isomerase Associated 5 (PDIA5) (AA 22-262) antibodyPDIA5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Disulfide Isomerase Associated 5 (PDIA5) (AA 1-519) antibodyPDIA5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Disulfide Isomerase Associated 5 (PDIA5) antibodyPDIA5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Disulfide Isomerase Associated 5 (PDIA5) (AA 31-130) antibodyPDIA5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Disulfide Isomerase Associated 5 (PDIA5) (AA 22-140) antibodyPDIA5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hartz, P. A. Personal Communication. Baltimore, Md. 5/9/2016. 2. Hayano, T., Kikuchi, M. Molecular cloning of the cDNA encoding a novel protein disulfide isomerase-related protein (PDIR). FEBS Lett. 372: 210-214, 1995. 3. Higa, A., Taouji, S., Lhomond, S., Jensen, D., Fernandez-Zapico, M. E., Simpson, J. C., Pasquet, J.-M., Schekman, R., Chevet, E. Endoplasmic reticulum stress-activated transcription factor ATF6-alpha requires the disulfide isomerase PDIA5 to modulate chemoresistance. Molec. Cell. Biol. 34: 1839-1849, 2014. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- PDIA5 (Protein Disulfide Isomerase Associated 5 (PDIA5))
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别名
- PDIA5
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背景
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Synonyms: Interleukin-36 alpha, FIL1 epsilon, Interleukin-1 epsilon, IL-1 epsilon, Interleukin-1 family member 6, IL-1F6, IL36A, FIL1E, IL1E, IL1F6
Tissue Specificity: Expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. Predominantly expressed in skin keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Increased in lesional psoriasis skin.
Background: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, three catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. The N-terminal TRX-like domain is the primary binding site for the major ER chaperone calreticulin and possibly other proteins and substrates as well. Alternative splicing results in multiple protein- and non-protein-coding transcript variants.
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分子量
- 60 kDa
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基因ID
- 10954
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UniProt
- Q14554
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途径
- Maintenance of Protein Location, Cell RedoxHomeostasis
抗原
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