Dynamin 1-Like 抗体 (AA 452-736)
Quick Overview for Dynamin 1-Like 抗体 (AA 452-736) (ABIN7601785)
抗原
See all Dynamin 1-Like (DNM1L) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 452-736
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原理
- Anti-DRP1/DNM1L Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-DRP1/DNM1L Antibody Picoband® (ABIN7601785). Tested in ELISA, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human DRP1/DNM1L recombinant protein (Position: Q452-W736).
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亚型
- IgG
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anti-Dynamin 1-Like (DNM1L) (AA 69-213) antibody
DNM1L 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4A4C7 unconjugated
anti-Dynamin 1-Like (DNM1L) (AA 69-213) antibodyDNM1L 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 4E11B11 unconjugated
anti-Dynamin 1-Like (DNM1L) (AA 1-710) antibodyDNM1L 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3B5 unconjugated
anti-Dynamin 1-Like (DNM1L) antibodyDNM1L 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2E7 unconjugated
anti-Dynamin 1-Like (DNM1L) antibodyDNM1L 适用: 人, 小鼠, 大鼠, 猴, 犬 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4F6 unconjugated
anti-Dynamin 1-Like (DNM1L) antibodyDNM1L 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 3F3 unconjugated
anti-Dynamin 1-Like (DNM1L) (AA 411-710) antibodyDNM1L 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dynamin 1-Like (DNM1L) (AA 496-710) antibodyDNM1L 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dynamin 1-Like (DNM1L) (C-Term) antibodyDNM1L 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dynamin 1-Like (DNM1L) (pSer637) antibodyDNM1L 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Barbet, F., Hakiki, S., Orssaud, C., Gerber, S., Perrault, I., Hanein, S., Ducroq, D., Dufier, J.-L., Munnich, A., Kaplan, J., Rozet, J.-M. A third locus for dominant optic atrophy on chromosome 22q. (Letter) J. Med. Genet. 42: e1, 2005. Note: Electronic Article. 2. Bras, M., Yuste, V. J., Roue, G., Barbier, S., Sancho, P., Virely, C., Rubio, M., Baudet, S., Esquerda, J. E., Merle-Beral, H., Sarfati, M., Susin, S. A. Drp1 mediates caspase-independent type III cell death in normal and leukemic cells. Molec. Cell. Biol. 27: 7073-7088, 2007. 3. Chang, C.-R., Manlandro, C. M., Arnoult, D., Stadler, J., Posey, A. E., Hill, R. B., Blackstone, C. A lethal de novo mutation in the middle domain of the dynamin-related GTPase Drp1 impairs higher order assembly and mitochondrial division. J. Biol. Chem. 285: 32494-32503, 2010. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Dynamin 1-Like (DNM1L)
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别名
- DNM1L
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背景
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Synonyms: Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, L-CA, T200, CD45, PTPRC, CD45
Tissue Specificity: Isoform 1: Detected in thymocytes. Isoform 2: Detected in thymocytes. Isoform 3: Detected in thymocytes. Isoform 4: Not detected in thymocytes. Isoform 5: Detected in thymocytes. Isoform 6: Not detected in thymocytes. Isoform 7: Detected in thymocytes. Isoform 8: Not detected in thymocytes.
Background: Dynamin-1-like protein is a GTPase that regulates mitochondrial fission. In humans, dynamin-1-like protein, which is typically referred to as dynamin-related protein 1 (Drp1), is encoded by the DNM1L gene. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.
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分子量
- 75 kDa
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基因ID
- 10059
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UniProt
- O00429
抗原
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