RAPGEF3 抗体 (AA 451-698)
Quick Overview for RAPGEF3 抗体 (AA 451-698) (ABIN7601784)
抗原
See all RAPGEF3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 451-698
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原理
- Anti-Epac1/RAPGEF3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Epac1/RAPGEF3 Antibody Picoband® (ABIN7601784). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Epac1/RAPGEF3 recombinant protein (Position: E451-D698).
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亚型
- IgG
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anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (AA 1-881) antibody
RAPGEF3 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (AA 772-881) antibodyRAPGEF3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E5 unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (C-Term) antibodyRAPGEF3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (AA 1-200) antibodyRAPGEF3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (AA 301-400) antibodyRAPGEF3 适用: 人, 大鼠 ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (AA 772-881) antibodyRAPGEF3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (C-Term) antibodyRAPGEF3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (AA 359-408) antibodyRAPGEF3 适用: 人, 小鼠, 大鼠, 马, Cow, 犬, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (AA 107-156) antibodyRAPGEF3 适用: 人, 小鼠, 大鼠, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (C-Term) antibodyRAPGEF3 适用: 人, 小鼠, 大鼠, Cow, 犬 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat, Monkey
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. de Rooij, J., Zwartkruis, F. J. T., Verheijen, M. H. G., Cool, R. H., Nijman, S. M. B., Wittinghofer, A., Bos, J. L. Epac is a Rap1 guanine-nucleotide-exchange factor ly activated by cyclic AMP. Nature 396: 474-477, 1998. 2. Dodge-Kafka, K. L., Soughayer, J., Pare, G. C., Michel, J. J. C., Langeberg, L. K., Kapiloff, M. S., Scott, J. D. The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways. Nature 437: 574-578, 2005. 3. Kawasaki, H., Springett, G. M., Mochizuki, N., Toki, S., Nakaya, M., Matsuda, M., Housman, D. E., Graybiel, A. M. A family of cAMP-binding proteins that ly activate Rap1. Science 282: 2275-2279, 1998. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- RAPGEF3 (Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3))
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别名
- RAPGEF3
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背景
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Synonyms: Fatty acid-binding protein, liver, Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, L-FABP, Squalene- and sterol-carrier protein, SCP, Z-protein, p14, Fabp1
Tissue Specificity: Expressed in lung cancers, including adenocarcinoma, squamous cell carcinoma and small-cell carcinoma. Widely expressed. Expressed in fetal kidney, liver, lung and brain. In adult highest expression in heart and placenta.
Background: Rap guanine nucleotide exchange factor 3 also known as exchange factor ly activated by cAMP 1 (EPAC1) or cAMP-regulated guanine nucleotide exchange factor I (cAMP-GEFI) is a protein that in humans is encoded by the RAPGEF3 gene. As the name suggests, EPAC proteins (EPAC1 and EPAC2) are a family of intracellular sensors for cAMP, and function as nucleotide exchange factors for the Rap subfamily of RAS-like small GTPases.
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分子量
- 104 kDa
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基因ID
- 10411
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UniProt
- O95398
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途径
- cAMP Metabolic Process
抗原
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