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Filamin A 抗体 (AA 451-638)

This anti-Filamin A antibody is a 小鼠 单克隆 antibody detecting Filamin A in WB, IHC 和 IF. Suitable for 人.
产品编号 ABIN7601783
发货至: 中国

Quick Overview for Filamin A 抗体 (AA 451-638) (ABIN7601783)

抗原

See all Filamin A (FLNA) 抗体
Filamin A (FLNA) (Filamin A, alpha (FLNA))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Filamin A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

克隆位点

3F8
  • 抗原表位

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    AA 451-638

    原理

    Anti-Filamin A/FLNA Antibody (monoclonal, 3F8)

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Filamin A/FLNA Antibody (monoclonal, 3F8) (ABIN7601783). Tested in IF, IHC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Filamin A/FLNA recombinant protein (Position: E451-Q638).

    亚型

    IgG1
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunofluorescence, 5 μg/mL, Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    Filamin A (FLNA) (Filamin A, alpha (FLNA))

    别名

    FLNA

    背景

    Synonyms: T-cell surface glycoprotein CD5, Lymphocyte antigen T1/Leu-1, CD5, CD5, LEU1

    Tissue Specificity: Brain, liver, placenta, lymphocytes and erythrocytes.

    Background: Filamin A, alpha (FLNA) is a protein that in humans is encoded by the FLNA gene. It is mapped to Xq28. The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.

    分子量

    281 kDa

    UniProt

    P21333

    途径

    TCR Signaling, Maintenance of Protein Location
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