Filamin A 抗体 (AA 451-638)
Quick Overview for Filamin A 抗体 (AA 451-638) (ABIN7601783)
抗原
See all Filamin A (FLNA) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 451-638
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原理
- Anti-Filamin A/FLNA Antibody Picoband® (monoclonal, 3F8)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Filamin A/FLNA Antibody Picoband® (monoclonal, 3F8) (ABIN7601783). Tested in IF, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Filamin A/FLNA recombinant protein (Position: E451-Q638).
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亚型
- IgG1
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anti-Filamin A, alpha (FLNA) (AA 2-274) antibody
FLNA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Filamin A, alpha (FLNA) antibodyFLNA 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Filamin A, alpha (FLNA) (AA 1-838) antibodyFLNA 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 4E10-1B2 unconjugated
anti-Filamin A, alpha (FLNA) (pSer2152) antibodyFLNA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Filamin A, alpha (FLNA) (AA 1819-2068) antibodyFLNA 适用: 人 WB, IHC, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Filamin A, alpha (FLNA) (AA 1234-1462) antibodyFLNA 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Filamin A, alpha (FLNA) antibodyFLNA 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Filamin A, alpha (FLNA) (AA 1-838) antibodyFLNA 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3B6-1D10 unconjugated
anti-Filamin A, alpha (FLNA) (AA 1025-1054) antibodyFLNA 适用: 人 WB, IHC (p), IF, FACS 宿主: 兔 Polyclonal RB14246 unconjugated
anti-Filamin A, alpha (FLNA) (AA 1-839) antibodyFLNA 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4E10-1B2 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
1. Gorlin JB, Henske E, Warren ST, Kunst CB, D'Urso M, Palmieri G, Hartwig JH, Bruns G, Kwiatkowski DJ (October 1993). "Actin-binding protein (ABP-280) filamin gene (FLN) maps telomeric to the color vision locus (R/GCP) and centromeric to G6PD in Xq28". Genomics. 17 (2): 496-8. 2. Robertson SP, Twigg SR, Sutherland-Smith AJ, Biancalana V, Gorlin RJ, Horn D, Kenwrick SJ, Kim CA, Morava E, Newbury-Ecob R, Orstavik KH, Quarrell OW, Schwartz CE, Shears DJ, Suri M, Kendrick-Jones J, Wilkie AO (March 2003). "Localized mutations in the gene encoding the cytoskeletal protein filamin A cause diverse malformations in humans". Nat Genet. 33 (4): 487-91. 3. Gräber P, Witt HT (February 1976). "Relations between the electrical potential, pH gradient, proton flux and phosphorylation in the photosynthetic membrane". Biochimica et Biophysica Acta. 423 (2): 141-63. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Filamin A (FLNA) (Filamin A, alpha (FLNA))
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别名
- FLNA
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背景
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Synonyms: T-cell surface glycoprotein CD5, Lymphocyte antigen T1/Leu-1, CD5, CD5, LEU1
Tissue Specificity: Brain, liver, placenta, lymphocytes and erythrocytes.
Background: Filamin A, alpha (FLNA) is a protein that in humans is encoded by the FLNA gene. It is mapped to Xq28. The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
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分子量
- 281 kDa
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UniProt
- P21333
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途径
- TCR Signaling, Maintenance of Protein Location
抗原
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