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Nucleostemin 抗体 (AA 45-549)

This anti-Nucleostemin antibody is a 兔 多克隆 antibody detecting Nucleostemin in WB, ELISA, IHC, IF, FACS 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7601778
发货至: 中国

Quick Overview for Nucleostemin 抗体 (AA 45-549) (ABIN7601778)

抗原

See all Nucleostemin (GNL3) 抗体
Nucleostemin (GNL3) (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (GNL3))

适用

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人, 小鼠, 大鼠

宿主

  • 65
  • 6
  • 2

克隆类型

  • 61
  • 12
多克隆

标记

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This Nucleostemin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
  • 抗原表位

    • 15
    • 9
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    AA 45-549

    原理

    Anti-Nucleostemin/GNL3 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Nucleostemin/GNL3 Antibody Picoband® (ABIN7601778). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Nucleostemin/GNL3 recombinant protein (Position: R45-V549).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Charpentier, A. H., Bednarek, A. K., Daniel, R. L., Hawkins, K. A., Laflin, K. J., Gaddis, S., MacLeod, M. C., Aldaz, C. M. Effects of estrogen on global gene expression: identification of novel targets of estrogen action. Cancer Res. 60: 5977-5983, 2000. 2. Dai, M.-S., Sun, X.-X., Lu, H. Aberrant expression of nucleostemin activates p53 and induces cell cycle arrest via inhibition of MDM2. Molec. Cell. Biol. 28: 4365-4376, 2008. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 6/29/2012.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    Nucleostemin (GNL3) (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (GNL3))

    别名

    GNL3

    背景

    Synonyms: CD48 antigen,B-lymphocyte activation marker BLAST-1,BCM1 surface antigen,Leukocyte antigen MEM-102,SLAM family member 2,SLAMF2,Signaling lymphocytic activation molecule 2,TCT.1,CD48,CD48,BCM1, BLAST1,

    Background: Guanine nucleotide-binding protein-like 3, also known as nucleostemin, is a protein that in humans is encoded by the GNL3 gene. The protein encoded by this gene may interact with p53 and may be involved in tumorigenesis. The encoded protein also appears to be important for stem cell proliferation. This protein is found in both the nucleus and nucleolus. Three transcript variants encoding two different isoforms have been found for this gene.

    分子量

    65 kDa

    基因ID

    26354
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