PRR5 抗体 (AA 45-366)
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北京 101111
Quick Overview for PRR5 抗体 (AA 45-366) (ABIN7601773)
抗原
See all PRR5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 45-366
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原理
- Anti-PRR5 Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-PRR5 Antibody. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PRR5 recombinant protein (Position: S45-D366).
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- PRR5 (Proline Rich 5 (Renal) (PRR5))
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别名
- PRR5
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背景
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Background: This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.
Gene Full Name: proline rich 5
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分子量
- 39 kDa
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基因ID
- 55615
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UniProt
- P85299
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途径
- PI3K-Akt Signaling
抗原
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