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FOXRED2 抗体 (AA 44-623)

FOXRED2 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7601747
发货至: 中国
  • 抗原 See all FOXRED2 抗体
    FOXRED2 (FAD-Dependent Oxidoreductase Domain Containing 2 (FOXRED2))
    抗原表位
    • 5
    • 1
    • 1
    • 1
    AA 44-623
    适用
    人, 小鼠, 大鼠
    宿主
    • 8
    克隆类型
    • 8
    多克隆
    标记
    • 4
    • 2
    • 1
    • 1
    This FOXRED2 antibody is un-conjugated
    应用范围
    • 7
    • 3
    • 2
    • 1
    ELISA, Western Blotting (WB)
    原理
    Anti-FOXRED2 Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-FOXRED2 Antibody Picoband® (ABIN7601747). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human FOXRED2 recombinant protein (Position: Q44-Q623).
    亚型
    IgG
    Top Product
    Discover our top product FOXRED2 Primary Antibody
  • 应用备注
    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Hartz, P. A. Personal Communication. Baltimore, Md. 2/25/2011. 2. Riemer, J., Appenzeller-Herzog, C., Johansson, L., Bodenmiller, B., Hartmann-Petersen, R., Ellgaard, L. A luminal flavoprotein in endoplasmic reticulum-associated degradation. Proc. Nat. Acad. Sci. 106: 14831-14836, 2009.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原
    FOXRED2 (FAD-Dependent Oxidoreductase Domain Containing 2 (FOXRED2))
    别名
    FOXRED2 (FOXRED2 产品)
    背景

    Synonyms: Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/I, Histone H3/j, Histone H3/k, Histone H3/l, HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, H3FJ

    Tissue Specificity: Expressed in fetal brain, fetal lung, fetal liver, heart, brain, placenta, lung, liver, muscle, kidney and pancreas.

    Background: FOXRED2, also known as ERFAD, is an endoplasmic reticulum (ER) luminal flavoprotein which may function in ER associated degradation (ERAD). It has been proposed to bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation. Upon knockdown of FOXRED2, the degradation of the ERAD model substrate ribophorin 332 is delayed, and the overall level of polyubiquitinated cellular proteins is decreased. Defects in the related protein FOXRED1 are a cause of mitochondrial complex I deficiency (MT-C1D), suggesting the FOXRED2 may also play a role in MT-C1D.

    分子量
    80 kDa
    基因ID
    80020
    途径
    SARS-CoV-2 Protein Interactome
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