PNP 抗体 (AA 44-273)
Quick Overview for PNP 抗体 (AA 44-273) (ABIN7601738)
抗原
See all PNP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 44-273
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原理
- Anti-PNP Antibody Picoband®
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产品特性
- Anti-PNP Antibody Picoband® (ABIN7601738). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PNP recombinant protein (Position: Q44-Q273). Human PNP shares 86.5% and 87% amino acid (aa) sequence identity with mouse and rat PNP, respectively.
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anti-Purine Nucleoside Phosphorylase (PNP) (AA 161-189) antibody
PNP 适用: 人, 小鼠, 大鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 161-189), (Middle Region) antibodyPNP 适用: 人, 小鼠, 大鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 1-289) antibodyPNP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6E5 unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 1-289) antibodyPNP 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 1-289) antibodyPNP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 174-283) antibodyPNP 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 142-153) antibodyVerified PNP 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 68-289) antibodyPNP 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 1-289) antibodyPNP 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 145-178) antibodyPNP 适用: 人 WB 宿主: 兔 Polyclonal RB49601 unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Williams, S. R., Goddard, J. M., Martin, D. W., Jr. Human purine nucleoside phosphorylase cDNA sequence and genomic clone characterization. Nucleic Acids Res. 12: 5779-5787, 1984. 2. Frecker, M., Dallaire, L., Young, S. R., Chen, G. C. C., Simpson, N. E. Confirmation of regional assignment of nucleoside phosphorylase (NP) on chromosome 14 by gene dosage studies. Hum. Genet. 45: 167-173, 1978. 3. Markert, M. L., Finkel, B. D., McLaughlin, T. M., Watson, T. J., Collard, H. R., McMahon, C. P., Andrews, L. G., Barrett, M. J., Ward, F. E. Mutations in purine nucleoside phosphorylase deficiency. Hum. Mutat. 9: 118-121, 1997. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PNP (Purine Nucleoside Phosphorylase (PNP))
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别名
- PNP
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背景
- The PNP gene encodes purine nucleoside phosphorylase, an enzyme that catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. It is presented results from gene dosage studies consistent with assignment of the PNP locus to band 14q13. PNP is expressed in most tissues, with markedly greater expression in lymphoid tissues. Genetic deficiencies of PNP result in severely compromised T?lymphocyte function and neurologic dysfunction.
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分子量
- 32 kDa
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基因ID
- 4860
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UniProt
- P00491
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus
抗原
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