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PRPF8 抗体 (AA 433-2166)

This anti-PRPF8 antibody is a 兔 多克隆 antibody detecting PRPF8 in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN7601730
发货至: 中国

Quick Overview for PRPF8 抗体 (AA 433-2166) (ABIN7601730)

抗原

See all PRPF8 抗体
PRPF8 (PRP8 Pre-mRNA Processing Factor 8 (PRPF8))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This PRPF8 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 433-2166

    原理

    Anti-PRPF8 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-PRPF8 Antibody Picoband® (ABIN7601730). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PRPF8 recombinant protein (Position: E433-H2166).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse
    ELISA, 0.1-0.5 μg/mL, -
    1. Achsel, T., Ahrens, K., Brahms, H., Teigelkamp, S., Luhrmann, R. The human U5-220kD protein (hPrp8) forms a stable RNA-free complex with several U5-specific proteins, including an RNA unwindase, a homologue of ribosomal elongation factor EF-2, and a novel WD-40 protein. Molec. Cell. Biol. 18: 6756-6766, 1998. 2. Greenberg, J., Goliath, R., Beighton, P., Ramesar, R. A new locus for autosomal dominant retinitis pigmentosa on the short arm of chromosome 17. Hum. Molec. Genet. 3: 915-918, 1994. 3. Luo, H. R., Moreau, G. A., Levin, N., Moore, M. J. The human Prp8 protein is a component of both U2- and U12-dependent spliceosomes. RNA 5: 893-908, 1999.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    PRPF8 (PRP8 Pre-mRNA Processing Factor 8 (PRPF8))

    别名

    PRPF8

    背景

    Synonyms: Tumor necrosis factor receptor superfamily member 13C, B-cell maturation defect, B-cell-activating factor receptor, BAFF receptor, BAFF-R, BLyS receptor 3, CD268, Tnfrsf13c, Baffr, Bcmd, Br3

    Tissue Specificity: Highly expressed in spleen and testis, detected at lower levels in lung and thymus.

    Background: Pre-mRNA-processing-splicing factor 8 is a protein that in humans is encoded by the PRPF8 gene. Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.

    分子量

    250 kDa

    基因ID

    10594

    UniProt

    Q6P2Q9
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