PRPF8 抗体 (AA 433-2166)
Quick Overview for PRPF8 抗体 (AA 433-2166) (ABIN7601730)
抗原
See all PRPF8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 433-2166
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原理
- Anti-PRPF8 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-PRPF8 Antibody Picoband® (ABIN7601730). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PRPF8 recombinant protein (Position: E433-H2166).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Achsel, T., Ahrens, K., Brahms, H., Teigelkamp, S., Luhrmann, R. The human U5-220kD protein (hPrp8) forms a stable RNA-free complex with several U5-specific proteins, including an RNA unwindase, a homologue of ribosomal elongation factor EF-2, and a novel WD-40 protein. Molec. Cell. Biol. 18: 6756-6766, 1998. 2. Greenberg, J., Goliath, R., Beighton, P., Ramesar, R. A new locus for autosomal dominant retinitis pigmentosa on the short arm of chromosome 17. Hum. Molec. Genet. 3: 915-918, 1994. 3. Luo, H. R., Moreau, G. A., Levin, N., Moore, M. J. The human Prp8 protein is a component of both U2- and U12-dependent spliceosomes. RNA 5: 893-908, 1999. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PRPF8 (PRP8 Pre-mRNA Processing Factor 8 (PRPF8))
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别名
- PRPF8
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背景
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Synonyms: Tumor necrosis factor receptor superfamily member 13C, B-cell maturation defect, B-cell-activating factor receptor, BAFF receptor, BAFF-R, BLyS receptor 3, CD268, Tnfrsf13c, Baffr, Bcmd, Br3
Tissue Specificity: Highly expressed in spleen and testis, detected at lower levels in lung and thymus.
Background: Pre-mRNA-processing-splicing factor 8 is a protein that in humans is encoded by the PRPF8 gene. Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.
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分子量
- 250 kDa
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基因ID
- 10594
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UniProt
- Q6P2Q9
抗原
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