MTHFD1L 抗体 (AA 43-833)
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- 抗原 See all MTHFD1L 抗体
- MTHFD1L (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1-Like (MTHFD1L))
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抗原表位
- AA 43-833
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MTHFD1L antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
- 原理
- Anti-MTHFD1L Antibody Picoband®
- 交叉反应 （详细）
- No cross-reactivity with other proteins.
- 产品特性
- Anti-MTHFD1L Antibody Picoband® (ABIN7601728). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human MTHFD1L recombinant protein (Position: R43-V833).
- 亚型
- IgG
- Top Product
- Discover our top product MTHFD1L Primary Antibody
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anti-Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1-Like (MTHFD1L) (AA 759-978) antibody
MTHFD1L 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1-Like (MTHFD1L) (AA 801-899) antibodyMTHFD1L 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E8 unconjugated
anti-Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1-Like (MTHFD1L) (C-Term) antibodyMTHFD1L 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1-Like (MTHFD1L) (AA 535-538) antibodyVerified MTHFD1L 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1-Like (MTHFD1L) (AA 801-899) antibodyMTHFD1L 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1-Like (MTHFD1L) antibodyMTHFD1L 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Christensen, K. E., Patel, H., Kuzmanov, U., Mejia, N. R., MacKenzie, R. E. Disruption of the Mthfd1 gene reveals a monofunctional 10-formyltetrahydrofolate synthetase in mammalian mitochondria. J. Biol. Chem. 280: 7597-7602, 2005. 2. Momb, J., Lewandowski, J. P., Bryant, J. D., Fitch, R., Surman, D. R., Vokes, S. A., Appling, D. R. Deletion of Mthfd1l causes embryonic lethality and neural tube and craniofacial defects in mice. Proc. Nat. Acad. Sci. 110: 549-554, 2013. 3. Prasannan, P., Pike, S., Peng, K., Shane, B., Appling, D. R. Human mitochondrial C(1)-tetrahydrofolate synthase: gene structure, tissue distribution of the mRNA, and immunolocalization in Chinese hamster ovary cells. J. Biol. Chem. 278: 43178-43187, 2003. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- 抗原
- MTHFD1L (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1-Like (MTHFD1L))
- 别名
- MTHFD1L (MTHFD1L 产品)
- 背景
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Synonyms: ELAV-like protein 2, ELAV-like neuronal protein 1, Hu-antigen B, HuB, Nervous system-specific RNA-binding protein Hel-N1, ELAVL2, HUB
Tissue Specificity: Brain, neural-specific.
Background: Monofunctional C1-tetrahydrofolate synthase, mitochondrial also known as formyltetrahydrofolate synthetase, is an enzyme that in humans is encoded by the MTHFD1L gene (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like). The protein encoded by this gene is involved in the synthesis of tetrahydrofolate (THF) in the mitochondrion. THF is important in the de novo synthesis of purines and thymidylate and in the regeneration of methionine from homocysteine. Several transcript variants encoding different isoforms have been found for this gene.
- 分子量
- 106 kDa
- 基因ID
- 25902
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