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Syntaphilin 抗体 (AA 43-482)

This anti-Syntaphilin antibody is a 兔 多克隆 antibody detecting Syntaphilin in WB, ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7601724
发货至: 中国

Quick Overview for Syntaphilin 抗体 (AA 43-482) (ABIN7601724)

抗原

See all Syntaphilin (SNPH) 抗体
Syntaphilin (SNPH)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Syntaphilin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 43-482

    原理

    Anti-SNPH Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-SNPH Antibody Picoband® (ABIN7601724). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human SNPH recombinant protein (Position: Y43-Q482).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Lao, G., Scheuss, V., Gerwin, C. M., Su, Q., Mochida, S., Rettig, J., Sheng, Z.-H. Syntaphilin: a syntaxin-1 clamp that controls SNARE assembly. Neuron 25: 191-201, 2000. 2. Nagase, T., Ishikawa, K., Nakajima, D., Ohira, M., Seki, N., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. DNA Res. 4: 141-150, 1997.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    Syntaphilin (SNPH)

    别名

    SNPH

    背景

    Synonyms: Pannexin-2, PANX2

    Tissue Specificity: Expressed in fetal and adult brain. Also detected in fetal liver and skeletal muscle, but not in their adult counterparts.

    Background: Syntaphilin is a protein that in humans is encoded by the SNPH gene. Syntaxin-1, synaptobrevin/VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane-associated and inhibits SNARE complex formation by binding free syntaxin-1. Expression of this gene appears to be brain-specific. Alternative splicing results in multiple transcript variants encoding different isoforms.

    分子量

    70 kDa

    基因ID

    9751

    UniProt

    O15079

    途径

    Synaptic Vesicle Exocytosis
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