SIRT3 抗体 (AA 43-399)
Quick Overview for SIRT3 抗体 (AA 43-399) (ABIN7601721)
抗原
See all SIRT3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 43-399
-
原理
- Anti-SIRT3 Antibody Picoband®
-
产品特性
- Anti-SIRT3 Antibody Picoband® (ABIN7601721). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human SIRT3 recombinant protein (Position: R43-K399). Human SIRT3 shares 83.5% amino acid (aa) sequence identity with mouse SIRT3.
-
-
anti-Sirtuin 3 (SIRT3) (C-Term) antibody
SIRT3 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 3 (SIRT3) (AA 250-279), (C-Term) antibodySIRT3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB01967 unconjugated
anti-Sirtuin 3 (SIRT3) (AA 126-399) antibodySIRT3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 3 (SIRT3) (AA 127-303) antibodySIRT3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 3 (SIRT3) (AA 155-290) antibodySIRT3 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 6B2A1 unconjugated
anti-Sirtuin 3 (SIRT3) (AA 304-334), (C-Term) antibodySIRT3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB25945 unconjugated
anti-Sirtuin 3 (SIRT3) (AA 304-334) antibodySIRT3 适用: 人, 小鼠, Hamster WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 3 (SIRT3) (AA 250-279) antibodySIRT3 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 3 (SIRT3) (AA 5-257) antibodySIRT3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 3 (SIRT3) (AA 20-130) antibodySIRT3 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Ahn, B.-H., Kim, H.-S., Song, S., Lee, I. H., Liu, J., Vassilopoulos, A., Deng, C.-X., Finkel, T. A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis. Proc. Nat. Acad. Sci. 105: 14447-14452, 2008. 2. Bellizzi, D., Rose, G., Cavalcante, P., Covello, G., Dato, S., De Rango, F., Greco, V., Maggiolini, M., Feraco, E., Mari, V., Franceschi, C., Passarino, G., De Benedictis, G. A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages. Genomics 85: 258-263, 2005. 3. Frye, R. A. Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity. Biochem. Biophys. Res. Commun. 260: 273-279, 1999. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- SIRT3 (Sirtuin 3 (SIRT3))
-
别名
- SIRT3
-
背景
- NAD-dependent deacetylase sirtuin-3, mitochondrial also known as SIRT3 is a protein that in humans is encoded by the SIRT3 gene. SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and prevent the formation of cancer cells. SIRT3 has far-reaching effects on nuclear gene expression, cancer, cardiovascular disease, neuroprotection, aging, and metabolic control.
-
分子量
- 28 kDa
-
基因ID
- 23410
抗原
-
