NRD1 抗体 (AA 427-967)
Quick Overview for NRD1 抗体 (AA 427-967) (ABIN7601708)
抗原
See all NRD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 427-967
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原理
- Anti-NRD1/NRDC Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-NRD1/NRDC Antibody Picoband® (ABIN7601708). Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NRD1/NRDC recombinant protein (Position: K427-R967).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Fumagalli, P., Accarino, M., Egeo, A., Scartezzini, P., Rappazzo, G., Pizzuti, A., Avvantaggiato, V., Simeone, A., Arrigo, G., Zuffardi, O., Ottolenghi, S., Taramelli, R. Human NRD convertase: a highly conserved metalloendopeptidase expressed at specific sites during development and in adult tissues. Genomics 47: 238-245, 1998. 2. Hospital, V., Prat, A., Joulie, C., Cherif, D., Day, R., Cohen, P. Human and rat testis express two mRNA species encoding variants of NRD convertase, a metalloendopeptidase of the insulinase family. Biochem. J. 327: 773-779, 1997. 3. Ohno, M., Hiraoka, Y., Matsuoka, T., Tomimoto, H., Takao, K., Miyakawa, T., Oshima, N., Kiyonari, H., Kimura, T., Kita, T., Nishi, E. Nardilysin regulates axonal maturation and myelination in the central and peripheral nervous system. Nature Neurosci. 12: 1506-1513, 2009. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- NRD1 (Nardilysin (N-Arginine Dibasic Convertase) (NRD1))
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别名
- NRDC
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背景
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Synonyms: Activator of 90 kDa heat shock protein ATPase homolog 1, AHA1, p38, AHSA1, C14orf3, HSPC322
Tissue Specificity: Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta.
Background: This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene.
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分子量
- 140 kDa
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基因ID
- 4898
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UniProt
- O43847
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途径
- Skeletal Muscle Fiber Development
抗原
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