SHROOM2 抗体 (AA 427-1138)
Quick Overview for SHROOM2 抗体 (AA 427-1138) (ABIN7601707)
抗原
See all SHROOM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 427-1138
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原理
- Anti-SHROOM2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SHROOM2 Antibody Picoband® (ABIN7601707). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SHROOM2 recombinant protein (Position: R427-H1138).
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亚型
- IgG
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anti-Shroom Family Member 2 (SHROOM2) (C-Term) antibody
SHROOM2 适用: 人 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Shroom Family Member 2 (SHROOM2) (AA 213-405) antibodySHROOM2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Shroom Family Member 2 (SHROOM2) (C-Term) antibodyVerified SHROOM2 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Shroom Family Member 2 (SHROOM2) (AA 1295-1344) antibodySHROOM2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 小鸡, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Shroom Family Member 2 (SHROOM2) (Middle Region) antibodySHROOM2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Dietz, M. L., Bernaciak, T. M., Vendetti, F., Kielec, J. M., Hildebrand, J. D. Differential actin-dependent localization modulates the evolutionarily conserved activity of Shroom family proteins. J. Biol. Chem. 281: 20542-20554, 2006. 2. Dinulos, M. B., Bassi, M. T., Rugarli, E. I., Chapman, V., Ballabio, A., Disteche, C. M. A new region of conservation is defined between human and mouse X chromosomes. Genomics 35: 244-247, 1996. 3. Schiaffino, M. V., Bassi, M. T., Rugarli, E. I., Renieri, A., Galli, L., Ballabio, A. Cloning of a human homologue of the Xenopus laevis APX gene from the ocular albinism type 1 critical region. Hum. Molec. Genet. 4: 373-382, 1995. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SHROOM2 (Shroom Family Member 2 (SHROOM2))
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别名
- SHROOM2
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背景
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Synonyms: Epigen,Epithelial mitogen,EPG,Epgn,
Background: Shroom family member 2 is a protein that in humans is encoded by the SHROOM2 gene. This gene represents the human homolog of Xenopus laevis apical protein (APX) gene, which is implicated in amiloride-sensitive sodium channel activity. It is expressed in endothelial cells and facilitates the formation of a contractile network within endothelial cells. Depletion of this gene results in an increase in endothelial sprouting, migration, and angiogenesis. This gene is highly expressed in the retina, and is a strong candidate for ocular albinism type 1 syndrome. Alternatively spliced transcript variants have been found for this gene.
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分子量
- 180 kDa
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基因ID
- 357
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UniProt
- Q13796
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途径
- Cell-Cell Junction Organization, Asymmetric Protein Localization
抗原
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