IGF2R 抗体 (AA 424-529)
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Quick Overview for IGF2R 抗体 (AA 424-529) (ABIN7601705)
抗原
See all IGF2R 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 424-529
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原理
- Anti-IGF2R Antibody (monoclonal, 4I11)
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-IGF2R Antibody.(monoclonal, 4I11)-1. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human IGF2R recombinant protein (Position: F424-R529).
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亚型
- IgG2a
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
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别名
- IGF2R
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背景
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Background: Insulin-like growth factor 2 receptor, also called IGF2R or I-MPR is a protein that in humans is encoded by the IGF2R gene. This gene is mapped to 6q25.3. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.
Gene Full Name: insulin like growth factor 2 receptor
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分子量
- 274 kDa
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基因ID
- 3482
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UniProt
- P11717
抗原
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