Calpain 3 抗体 (AA 42-764)
Quick Overview for Calpain 3 抗体 (AA 42-764) (ABIN7601700)
抗原
See all Calpain 3 (CAPN3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 42-764
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原理
- Anti-Calpain 3/CAPN3 Antibody Picoband®
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产品特性
- Anti-Calpain 3/CAPN3 Antibody Picoband® (ABIN7601700). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Calpain 3/CAPN3 recombinant protein (Position: I42-D764). Human CAPN3 shares 93.5% and 94.2% amino acid (aa) sequence identity with mouse and rat CAPN3, respectively.
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anti-Calpain 3 (CAPN3) (AA 602-821) antibody
CAPN3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calpain 3 (CAPN3) (AA 210-309) antibodyCAPN3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1B2 unconjugated
anti-Calpain 3 (CAPN3) (AA 603-632), (C-Term) antibodyCAPN3 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18391 unconjugated
anti-Calpain 3 (CAPN3) (AA 582-821) antibodyCAPN3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calpain 3 (CAPN3) (AA 582-821) antibodyCAPN3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calpain 3 (CAPN3) antibodyCAPN3 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calpain 3 (CAPN3) antibodyCAPN3 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Calpain 3 (CAPN3) (AA 1-150) antibodyCAPN3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Calpain 3 (CAPN3) (C-Term) antibodyCAPN3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Blazquez, L., Azpitarte, M., Saenz, A., Goicoechea, M., Otaegui, D., Ferrer, X., Illa, I., Gutierrez-Rivas, E., Vilchez, J. J., Lopez de Munain, A. Characterization of novel CAPN3 isoforms in white blood cells: an alternative approach for limb-girdle muscular dystrophy 2A diagnosis. Neurogenetics 9: 173-182, 2008. 2. Canki-Klain, N., Milic, A., Kovac, B., Trlaja, A., Grgicevic, D., Zurak, N., Fardeau, M., Leturcq, F., Kaplan, J.-C., Urtizberea, J. A., Politano, L., Piluso, G., Feingold, J. Prevalence of the 550delA mutation in calpainopathy (LGMD 2A) in Croatia. Am. J. Med. Genet. 125A: 152-156, 2004. Note: Erratum: Am. J. Med. Genet. 130A: 218 only, 2004. 3. Duno, M., Sveen, M.-L., Schwartz, M., Vissing, J. cDNA analyses of CAPN3 enhances mutation detection and reveals a low prevalence of LGMD2A patients in Denmark. Europ. J. Hum. Genet. 16: 935-940, 2008. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Calpain 3 (CAPN3)
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别名
- Calpain 3/CAPN3
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背景
- Calpain-3 is a protein that in humans is encoded by the CAPN3 gene. Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.
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分子量
- 99 kDa
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基因ID
- 825
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UniProt
- P20807
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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