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SH2D4A 抗体 (AA 42-454)

This anti-SH2D4A antibody is a 兔 多克隆 antibody detecting SH2D4A in WB, ELISA, IHC, IF, FACS 和 ICC. Suitable for 人 和 大鼠.
产品编号 ABIN7601695
发货至: 中国

Quick Overview for SH2D4A 抗体 (AA 42-454) (ABIN7601695)

抗原

See all SH2D4A 抗体
SH2D4A (SH2 Domain Containing 4A (SH2D4A))

适用

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人, 大鼠

宿主

  • 17
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  • 1

克隆类型

  • 20
  • 1
多克隆

标记

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This SH2D4A antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
  • 抗原表位

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    • 4
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    AA 42-454

    原理

    Anti-SH2D4A Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-SH2D4A Antibody Picoband® (ABIN7601695). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human SH2D4A recombinant protein (Position: R42-E454).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Dai, S., Zhao, Y., Ding, Q. A novel member of SH2A signaling protein family: cloning and characterization of SH2 gene. Chinese J. Med. Genet. 19: 458-462, 2002. 2. Lapinski, P. E., Oliver, J. A., Kamen, L. A., Hughes, E. D., Saunders, T. L., King, P. D. Genetic analysis of SH2D4A, a novel adapter protein related to T cell-specific adapter and adapter protein in lymphocytes of unknown function, reveals a redundant function in T cells. J. Immun. 181: 2019-2027, 2008. 3. Li, T., Li, W., Lu, J., Liu, H., Li, Y., Zhao, Y. SH2D4A regulates cell proliferation via the ER-alpha/PLC-gamma/PKC pathway. BMB Rep. 42: 516-522, 2009.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    SH2D4A (SH2 Domain Containing 4A (SH2D4A))

    别名

    SH2D4A

    背景

    Synonyms: Tudor domain-containing protein 3, TDRD3

    Tissue Specificity: Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

    Background: SH2 domain-containing protein 4A is a protein that in humans is encoded by the SH2D4A gene. Using exon trapping and exon linking at chromosome 8p22 cloned SH2D4A, which they called SH2A. The deduced 454-amino acid protein contains a single SH2 domain. RT-PCR and Northern blot analysis detected ubiquitous expression of 3 SH2A transcripts, as well as aberrant expression in some cancer cell lines. Dai et al. (2002) concluded that SH2A is a docking protein that may be involved in signal transduction.

    分子量

    50 kDa

    基因ID

    63898

    UniProt

    Q9H788
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