HSD17B8 抗体 (AA 42-244)
Quick Overview for HSD17B8 抗体 (AA 42-244) (ABIN7601689)
抗原
See all HSD17B8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 42-244
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原理
- Anti-HSD17B8 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-HSD17B8 Antibody Picoband® (ABIN7601689). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HSD17B8 recombinant protein (Position: D42-D244).
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亚型
- IgG
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anti-Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8) antibody
HSD17B8 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8) (AA 28-127) antibodyHSD17B8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4F1 unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8) (AA 57-261) antibodyHSD17B8 适用: 人, 犬 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 6H2 unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8) (AA 1-261) antibodyHSD17B8 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8) (AA 1-261) antibodyHSD17B8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8) (AA 1-261) antibodyHSD17B8 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8) (AA 33-67), (N-Term) antibodyHSD17B8 适用: 人 WB 宿主: 兔 Polyclonal RB48812 unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8) antibodyHSD17B8 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8) (AA 51-100) antibodyHSD17B8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Ando, A., Kikuti, Y. Y., Shigenari, A., Kawata, H., Okamoto, N., Shiina, T., Chen, L., Ikemura, T., Abe, K., Kimura, M., Inoko, H. cDNA cloning of the human homologues of the mouse Ke4 and Ke6 genes at the centromeric end of the human MHC region. Genomics 35: 600-602, 1996. 2. Aziz, N., Anderson, E., Lee, G. Y., Woo, D. D. L. Arrested testis development in the cpk mouse may be the result of abnormal steroid metabolism. Molec. Cell. Endocr. 171: 83-88, 2001. 3. Chen, Z., Kastaniotis, A. J., Miinalainen, I. J., Rajaram, V., Wierenga, R. K., Hiltunen, J. K. 17-beta-hydroxysteroid dehydrogenase type 8 and carbonyl reductase type 4 assemble as a ketoacyl reductase of human mitochondrial FAS. FASEB J. 23: 3682-3691, 2009. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))
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别名
- HSD17B8
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背景
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Synonyms: Transcription factor Sp6, Krueppel-like factor 14, SP6, KLF14
Tissue Specificity: Ubiquitous.
Background: Estradiol 17 beta-dehydrogenase 8 is an enzyme that in humans is encoded by the HSD17B8 gene. In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.
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分子量
- 34 kDa
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基因ID
- 7923
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UniProt
- Q92506
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途径
- Steroid Hormone Biosynthesis
抗原
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