Glucuronidase beta 抗体 (AA 416-651)
Quick Overview for Glucuronidase beta 抗体 (AA 416-651) (ABIN7601685)
抗原
See all Glucuronidase beta (GUSB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 416-651
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原理
- Anti-beta glucuronidase/GUSB Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-beta glucuronidase/GUSB Antibody Picoband® (ABIN7601685). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human beta glucuronidase/GUSB recombinant protein (Position: Q416-T651).
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亚型
- IgG
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anti-Glucuronidase, beta (GUSB) (AA 382-651) antibody
GUSB 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glucuronidase, beta (GUSB) (Internal Region) antibodyGUSB 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glucuronidase, beta (GUSB) (AA 335-362) antibodyGUSB 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24036 unconjugated
anti-Glucuronidase, beta (GUSB) (AA 589-651) antibodyGUSB 适用: 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glucuronidase, beta (GUSB) antibodyGUSB 适用: E. coli WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Glucuronidase, beta (GUSB) (AA 451-649) antibodyGUSB 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glucuronidase, beta (GUSB) (AA 451-648) antibodyGUSB 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glucuronidase, beta (GUSB) (AA 382-651) antibodyGUSB 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glucuronidase, beta (GUSB) antibodyGUSB 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glucuronidase, beta (GUSB) (AA 1-651) antibodyGUSB 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Kreamer, B. L., Siegel, F. L., Gourley, G. R. A novel inhibitor of beta-glucuronidase: L-aspartic acid. Pediat. Res. 50: 460-466, 2001. 2. Miller, R. D., Hoffmann, J. W., Powell, P. P., Kyle, J. W., Shipley, J. M., Bachinsky, D. R., Sly, W. S. Cloning and characterization of the human beta-glucuronidase gene. Genomics 7: 280-283, 1990. 3. Tomatsu, S., Orii, K. O., Vogler, C., Grubb, J. H., Snella, E. M., Gutierrez, M. A., Dieter, T., Sukegawa, K., Orii, T., Kondo, N., Sly, W. S. Missense models [Gus(tm(E536A)Sly), Gus(tm(E536Q)Sly), and Gus(tm(L175F)Sly)] of murine mucopolysaccharidosis type VII produced by targeted mutagenesis. Proc. Nat. Acad. Sci. 99: 14982-14987, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Glucuronidase beta (GUSB) (Glucuronidase, beta (GUSB))
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别名
- GUSB
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背景
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Synonyms: Beta-glucuronidase, Beta-G1, GUSB
Tissue Specificity: Broadly expressed with higher expression in heart.
Background: Beta-glucuronidases are members of the glycosidase family of enzymes that catalyze breakdown of complex carbohydrates. This gene encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. Alternative splicing results in multiple transcript variants. There are many pseudogenes of this locus in the human genome.
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分子量
- 82 kDa
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基因ID
- 2990
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UniProt
- P08236
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途径
- Glycosaminoglycan Metabolic Process
抗原
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