GIGYF2 抗体 (AA 413-1299)
Quick Overview for GIGYF2 抗体 (AA 413-1299) (ABIN7601679)
抗原
See all GIGYF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 413-1299
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原理
- Anti-GIGYF2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-GIGYF2 Antibody Picoband® (ABIN7601679). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GIGYF2 recombinant protein (Position: R413-Y1299).
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亚型
- IgG
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anti-GRB10 Interacting GYF Protein 2 (GIGYF2) (AA 835-869) antibody
GIGYF2 适用: 人 WB 宿主: 兔 Polyclonal RB54694 unconjugated
anti-GRB10 Interacting GYF Protein 2 (GIGYF2) (AA 375-425) antibodyGIGYF2 适用: 人 WB, IHC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GRB10 Interacting GYF Protein 2 (GIGYF2) (AA 350-500) antibodyGIGYF2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GRB10 Interacting GYF Protein 2 (GIGYF2) (N-Term) antibodyGIGYF2 适用: 人, 小鼠, 犬, 豚鼠, 马, 大鼠, 兔, Cow WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bras, J., Simon-Sanchez, J., Federoff, M., Morgadinho, A., Januario, C., Ribeiro, M., Cunha, L., Oliveira, C., Singleton, A. B. Lack of replication of association between GIGYF2 variants and Parkinson disease. Hum. Molec. Genet. 18: 341-346, 2009. 2. Giovannone, B., Lee, E., Laviola, L., Giorgino, F., Cleveland, K. A., Smith, R. J. Two novel proteins that are linked to insulin-like growth factor (IFG-I) receptors by the Grb10 adapter and modulate IGF-I signaling. J. Biol. Chem. 278: 31564-31573, 2003. 3. Giovannone, B., Tsiaras, W. G., de la Monte, S., Klysik, J., Lautier, C., Karashchuk, G., Goldwurm, S., Smith, R. J. GIGYF2 gene disruption in mice results in neurodegeneration and altered insulin-like growth factor signaling. Hum. Molec. Genet. 18: 4629-4639, 2009. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- GIGYF2 (GRB10 Interacting GYF Protein 2 (GIGYF2))
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别名
- GIGYF2
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背景
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Synonyms: Calretinin, CR, 29 kDa calbindin, CALB2, CAB29
Tissue Specificity: Brain.
Background: This gene contains CAG trinucleotide repeats and encodes a protein containing several stretches of polyglutamine residues. The encoded protein may be involved in the regulation of tyrosine kinase receptor signaling. This gene is located in a chromosomal region that was genetically linked to Parkinson disease type 11, and mutations in this gene were thought to be causative for this disease. However, more recent studies in different populations have been unable to replicate this association. Alternative splicing results in multiple transcript variants.
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分子量
- 180 kDa
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基因ID
- 26058
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UniProt
- Q6Y7W6
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途径
- Feeding Behaviour, SARS-CoV-2 Protein Interactome
抗原
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