ITGA4 抗体 (AA 41-963)
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Quick Overview for ITGA4 抗体 (AA 41-963) (ABIN7601675)
抗原
See all ITGA4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 41-963
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原理
- Anti-Integrin Alpha 4/Itga4 Antibody
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Mouse Itga4 shares 85.2% amino acid (aa) sequence identity with human Itga4.
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产品特性
- Anti-Integrin Alpha 4/Itga4 Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse Integrin Alpha 4/Itga4 recombinant protein (Position: Y41-D963). Mouse Itga4 shares 85.2% amino acid (aa) sequence identity with human Itga4.
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- ITGA4 (Integrin alpha 4 (ITGA4))
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别名
- Itga4
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背景
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Background: CD49d is an integrin alpha subunit. It makes up half of the α4β1 lymphocyte homing receptor. The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.
Gene Full Name: integrin alpha 4
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分子量
- 150-180 kDa
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基因ID
- 16401
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UniProt
- Q00651
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途径
- Integrin Complex
抗原
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