ADAM15 抗体 (AA 41-456)
Quick Overview for ADAM15 抗体 (AA 41-456) (ABIN7601669)
抗原
See all ADAM15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 41-456
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原理
- Anti-ADAM15 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-ADAM15 Antibody Picoband® (ABIN7601669). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ADAM15 recombinant protein (Position: R41-R456).
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亚型
- IgG
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anti-ADAM Metallopeptidase Domain 15 (ADAM15) antibody
ADAM15 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-ADAM Metallopeptidase Domain 15 (ADAM15) (AA 1-225) antibodyADAM15 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 15 (ADAM15) (N-Term) antibodyADAM15 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 15 (ADAM15) antibodyADAM15 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 15 (ADAM15) (Middle Region) antibodyADAM15 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 15 (ADAM15) (AA 207-452) antibodyADAM15 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 15 (ADAM15) (AA 37-72) antibodyADAM15 适用: 人 WB 宿主: 兔 Polyclonal RB52706 unconjugated
anti-ADAM Metallopeptidase Domain 15 (ADAM15) antibody (Biotin)ADAM15 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal Biotin
anti-ADAM Metallopeptidase Domain 15 (ADAM15) antibody (FITC)ADAM15 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal FITC
anti-ADAM Metallopeptidase Domain 15 (ADAM15) antibody (HRP)ADAM15 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal HRP
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Herren, B., Raines, E. W., Ross, R. Expression of a disintegrin-like protein in cultured human vascular cells and in vivo. FASEB J. 11: 173-180, 1997. 2. Horiuchi, K., Weskamp, G., Lum, L., Hammes, H.-P., Cai, H., Brodie, T. A., Ludwig, T., Chiusaroli, R., Baron, R., Preissner, K. T., Manova, K., Blobel, C. P. Potential role for ADAM15 in pathological neovascularization in mice. Molec. Cell. Biol. 23: 5614-5624, 2003. 3. Karkkainen, I., Karhu, R., Huovila, A.-P. J. Assignment of the ADAM15 gene to human chromosome band 1q21.3 by in situ hybridization. Cytogenet. Cell Genet. 88: 206-207, 2000. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))
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别名
- ADAM15
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背景
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Synonyms: Disintegrin and metalloproteinase domain-containing protein 15, ADAM 15, Metalloprotease RGD disintegrin protein, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15, MDC-15, Metargidin, ADAM15, MDC15
Tissue Specificity: Expressed in colon and small intestine. Expressed in airway smooth muscle and glomerular mesangial cells (at protein level). Ubiquitously expressed. Overexpressed in atherosclerotic lesions. Constitutively expressed in cultured endothelium and smooth muscle. Expressed in chondrocytes. Expressed in airway smooth muscle and glomerular mesangial cells.
Background: Disintegrin and metalloproteinase domain-containing protein 15 is an enzyme that in humans is encoded by the ADAM15 gene. This gene is mapped to 1q21.3. The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
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分子量
- 100 kDa
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基因ID
- 8751
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UniProt
- Q13444
抗原
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