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PCCA 抗体 (AA 403-728)

This anti-PCCA antibody is a 兔 多克隆 antibody detecting PCCA in WB, ELISA, IHC 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7601658
发货至: 中国

Quick Overview for PCCA 抗体 (AA 403-728) (ABIN7601658)

抗原

See all PCCA 抗体
PCCA (Propionyl CoA Carboxylase, alpha Polypeptide (PCCA))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This PCCA antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • 抗原表位

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    AA 403-728

    原理

    Anti-PCCA Antibody Picoband®

    交叉反应 (详细)

    No cross reactivity with other proteins.

    产品特性

    Anti-PCCA Antibody Picoband® (ABIN7601658). Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PCCA recombinant protein (Position: E403-E728). Human PCCA shares 89.6% and 89% amino acid (aa) sequence identity with mouse and rat PCCA, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry, 2-5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Bowcock, A. M., Gerken, S. C., Barnes, R. I., Shiang, R., Jabs, E. W., Warren, A. C., Antonarakis, S., Retief, A. E., Vergnaud, G., Leppert, M., Lalouel, J.-M., White, R. L., Cavalli-Sforza, L. L. The CEPH consortium linkage map of human chromosome 13. Genomics 16: 486-496, 1993. 2. Campeau, E., Dupuis, L., Leclerc, D., Gravel, R. A. Detection of a normally rare transcript in propionic acidemia patients with mRNA destabilizing mutations in the PCCA gene. Hum. Molec. Genet. 8: 107-113, 1999. 3. Childs, B., Nyhan, W. L., Borden, M., Bard, L., Cooke, R. E. Idiopathic hyperglycinemia and hyperglycinuria: a new disorder of amino acid metabolism. Pediatrics 27: 522-538, 1961.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    PCCA (Propionyl CoA Carboxylase, alpha Polypeptide (PCCA))

    别名

    PCCA

    背景

    Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

    Tissue Specificity: Expressed in all tissues.

    Background: The protein encoded by this gene is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA encodes the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia. Multiple transcript variants encoding different isoforms have been found for this gene.

    分子量

    70 kDa

    基因ID

    5095

    UniProt

    P05165

    途径

    Monocarboxylic Acid Catabolic Process
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