DBH 抗体 (AA 40-545)
Quick Overview for DBH 抗体 (AA 40-545) (ABIN7601651)
抗原
See all DBH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-545
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原理
- Anti-Dopamine beta Hydroxylase/DBH Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Dopamine beta Hydroxylase/DBH Antibody Picoband® (ABIN7601651). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Dopamine beta Hydroxylase/DBH recombinant protein (Position: S40-N545).
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亚型
- IgG
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anti-Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH) (AA 27-56) antibody
DBH 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH) (AA 34-64), (N-Term) antibodyDBH 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH) (AA 335-571) antibodyDBH 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH) (C-Term) antibodyDBH 适用: 人, 小鼠, 灵长类 WB, IHC, IHC (p) 宿主: 绵羊 Polyclonal unconjugated
anti-Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH) (N-Term) antibodyDBH 适用: 人, 灵长类 WB, IHC, IHC (p) 宿主: 绵羊 Polyclonal unconjugated
anti-Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH) (AA 437-448) antibodyVerified DBH 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH) (Internal Region) antibodyDBH 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH) (AA 150-250) antibodyDBH 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH) (N-Term) antibodyDBH 适用: 人 WB 宿主: 绵羊 Polyclonal unconjugated
anti-Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH) (C-Term) antibodyDBH 适用: 人 WB 宿主: 绵羊 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Rush RA, Geffen LB (1980). "Dopamine beta-hydroxylase in health and disease". Critical Reviews in Clinical Laboratory Sciences. 12 (3): 241-77. 2. Kaufman S, Bridgers WF, Baron J (1968). "The Mechanism of Action of Dopamine beta-Hydroxylase". Advances in Chemistry. 77, chapter 73: 172-176. 3. Friedman S, Kaufman S (May 1966). "An electron paramagnetic resonance study of 3,4-dihydroxyphenylethylamine beta-hydroxylase". The Journal of Biological Chemistry. 241 (10): 2256-9. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- DBH (Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH))
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别名
- DBH
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背景
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Synonyms: Dopamine beta-hydroxylase; Dopamine beta-monooxygenase; DBH
Tissue Specificity: Within the immune system initially reported to be selectively expressed in granulocytes (polymorphonuclear leukocytes [PMNs]). Also detected in macrophages mycobacterial granulomas. Expressed in group2 innate lymphoid cells (ILC2s) during lung disease.
Background: Dopamine beta-hydroxylase (DBH), also known as dopamine beta-monooxygenase, is an enzyme (EC1.14.17.1) that in humans is encoded by the DBH gene. Dopamine beta-hydroxylase catalyzes the chemical reaction. It is mapped to 9q34.2. The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. The encoded protein, expressed in neuroscretory vesicles and chromaffin granules of the adrenal medulla, catalyzes the conversion of dopamine to norepinephrine, which functions as both a hormone and as the main neurotransmitter of the sympathetic nervous system. The enzyme encoded by this gene exists exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide. Mutations in this gene cause dopamine beta-hydroxylate deficiency in human patients, characterized by deficits in autonomic and cardiovascular function, including hypotension and ptosis. Polymorphisms in this gene may play a role in a variety of psychiatric disorders.
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分子量
- 75 kDa
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基因ID
- 1621
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UniProt
- P09172
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途径
- Carbohydrate Homeostasis
抗原
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