SPRED2 抗体 (AA 40-298)
Quick Overview for SPRED2 抗体 (AA 40-298) (ABIN7601643)
抗原
See all SPRED2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 40-298
-
原理
- Anti-SPRED2 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-SPRED2 Antibody Picoband® (ABIN7601643). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human SPRED2 recombinant protein (Position: R40-R298).
-
亚型
- IgG
-
-
anti-Sprouty-Related, EVH1 Domain Containing 2 (SPRED2) (AA 120-219) antibody
SPRED2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6G8 unconjugated
anti-Sprouty-Related, EVH1 Domain Containing 2 (SPRED2) (AA 120-219) antibodySPRED2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Sprouty-Related, EVH1 Domain Containing 2 (SPRED2) (AA 120-300) antibodySPRED2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sprouty-Related, EVH1 Domain Containing 2 (SPRED2) (AA 120-219) antibodySPRED2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G11 unconjugated
anti-Sprouty-Related, EVH1 Domain Containing 2 (SPRED2) (AA 317-366) antibodySPRED2 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 斑马鱼, Bat, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Sprouty-Related, EVH1 Domain Containing 2 (SPRED2) (C-Term) antibodySPRED2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sprouty-Related, EVH1 Domain Containing 2 (SPRED2) (AA 1-418) antibodySPRED2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Sprouty-Related, EVH1 Domain Containing 2 (SPRED2) (C-Term) antibodySPRED2 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 斑马鱼, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bundschu, K., Knobeloch, K.-P., Ullrich, M., Schinke, T., Amling, M., Engelhardt, C. M., Renne, T., Walter, U., Schuh, K. Gene disruption of Spred-2 causes dwarfism. J. Biol. Chem. 280: 28572-28580, 2005. 2. Kato, R., Nonami, A., Taketomi, T., Wakioka, T., Kuroiwa, A., Matsuda, Y., Yoshimura, A. Molecular cloning of mammalian Spred-3 which suppresses tyrosine kinase-mediated Erk activation. Biochem. Biophys. Res. Commun. 302: 767-772, 2003. 3. Motta, M., Fasano, G., Gredy, S., Brinkmann, J., Bonnard, A. A., Simsek-Kiper, P. O., Gulec, E. Y., Essaddam, L., Utine, G. E., Guarnetti Prandi, I., Venditti, M., Pantaleoni, F., and 21 others. SPRED2 loss-of-function causes a recessive Noonan syndrome-like phenotype. Am. J. Hum. Genet. 108: 2112-2129, 2021. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- SPRED2 (Sprouty-Related, EVH1 Domain Containing 2 (SPRED2))
-
别名
- SPRED2
-
背景
-
Synonyms: Rho-related GTP-binding protein Rho6,Rho family GTPase 1,Rnd1,RND1,RHO6,
Tissue Specificity: Mostly expressed in brain and liver.
Background: Sprouty-related, EVH1 domain-containing protein 2 is a protein that in humans is encoded by the SPRED2 gene. SPRED2 is a member of the Sprouty (see SPRY1, MIM 602465)/SPRED family of proteins that regulate growth factor-induced activation of the MAP kinase cascade.
-
分子量
- 53 kDa
-
基因ID
- 200734
-
UniProt
- Q7Z698
抗原
-
