MED17 抗体 (AA 4-561)
Quick Overview for MED17 抗体 (AA 4-561) (ABIN7601629)
抗原
See all MED17 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 4-561
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原理
- Anti-MED17 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MED17 Antibody Picoband® (ABIN7601629). Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MED17 recombinant protein (Position: V4-E561).
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亚型
- IgG
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anti-Mediator Complex Subunit 17 (MED17) (AA 551-651) antibody
MED17 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4D4 unconjugated
anti-Mediator Complex Subunit 17 (MED17) antibodyMED17 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 17 (MED17) (N-Term) antibodyMED17 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB, IHC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 17 (MED17) (AA 411-651) antibodyMED17 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 17 (MED17) (Internal Region) antibodyMED17 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 17 (MED17) (AA 156-205) antibodyMED17 适用: 人, 大鼠, 犬, Cow, 豚鼠, 马, 兔, Bat, Hamster, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 17 (MED17) (AA 1-300) antibodyMED17 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 17 (MED17) (AA 181-280) antibodyMED17 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 17 (MED17) (AA 551-651) antibodyMED17 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Mediator Complex Subunit 17 (MED17) (Internal Region) antibodyMED17 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Donner, A. J., Szostek, S., Hoover, J. M., Espinosa, J. M. CDK8 is a stimulus-specific positive coregulator of p53 target genes. Molec. Cell 27: 121-133, 2007. 2. Ito, M., Yuan, C.-X., Malik, S., Gu, W., Fondell, J. D., Yamamura, S., Fu, Z.-Y., Zhang, X., Qin, J., Roeder, R. G. Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators. Molec. Cell 3: 361-370, 1999. 3. Jiang, Y.-W., Veschambre, P., Erdjument-Bromage, H., Tempst, P., Conaway, J. W., Conaway, R. C., Kornberg, R. D. Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways. Proc. Nat. Acad. Sci. 95: 8538-8543, 1998. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MED17 (Mediator Complex Subunit 17 (MED17))
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别名
- MED17
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背景
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Synonyms: RNA binding protein fox-1 homolog 2, Fox-1 homolog B, Hexaribonucleotide-binding protein 2, RNA-binding motif protein 9, RNA-binding protein 9, Repressor of tamoxifen transcriptional activity, RBFOX2, FOX2, HRNBP2, RBM9, RTA
Tissue Specificity: Expressed in fetal brain. Highly expressed in brain and placenta. Lower levels in heart, liver, thymus, kidney and lung. Located to endothelial cells and neuronal cells of the suprachiasmatic nucleus (SCN). Also detected in endothelial cells of the heart, lung and kidney. In the brain, specifically expressed in the thalamus, hippocampus and amygdala.
Background: Mediator of RNA polymerase II transcription subunit 17 is an enzyme that in humans is encoded by the MED17 gene. The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
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分子量
- 73 kDa
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基因ID
- 9440
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
抗原
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