GCLM 抗体 (AA 4-263)
Quick Overview for GCLM 抗体 (AA 4-263) (ABIN7601616)
抗原
See all GCLM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 4-263
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原理
- Anti-GCLM Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-GCLM Antibody Picoband® (ABIN7601616). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GCLM recombinant protein (Position: D4-K263).
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亚型
- IgG
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anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 40-251) antibody
GCLM 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 246-274), (C-Term) antibodyGCLM 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB22980 unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 1-274), (Regulatory Subunit) antibodyGCLM 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 1-274) antibodyGCLM 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B8 unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 245-274), (C-Term) antibodyGCLM 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 1-274) antibodyGCLM 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (N-Term) antibodyGCLM 适用: 人, 小鼠, 大鼠, Pig WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 182-231) antibodyGCLM 适用: 人, 小鼠, 大鼠, Cow, 兔, 猴, 犬, 豚鼠, 马, 斑马鱼, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 1-274) antibodyGCLM 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (Middle Region) antibodyGCLM 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Arinami, T., Ohtsuki, T., Ishiguro, H., Ujike, H., Tanaka, Y., Morita, Y., Mineta, M., Takeichi, M., Yamada, S., Imamura, A., Ohara, K., Shibuya, H., and 40 others. Genomewide high-density SNP linkage analysis of 236 Japanese families supports the existence of schizophrenia susceptibility loci on chromosomes 1p, 14q, and 20p. Am. J. Hum. Genet. 77: 937-944, 2005. 2. Gipp, J. J., Bailey, H. H., Mulcahy, R. T. Cloning and sequencing of the cDNA for the light subunit of human liver gamma-glutamylcysteine synthetase and relative mRNA levels for heavy and light subunits in human normal tissues. Biochem. Biophys. Res. Commun. 206: 584-589, 1995. 3. Huang, C.-S., Anderson, M. E., Meister, A. Amino acid sequence and function of the light subunit of rat kidney gamma-glutamylcysteine synthetase. J. Biol. Chem. 268: 20578-20583, 1993. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))
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别名
- GCLM
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背景
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Synonyms: Caspase-4, CASP-4
Tissue Specificity: Widely expressed, including in thymus, lung and spleen (at protein level). Very low levels, if any, in the brain.
Background: Glutamate-cysteine ligase regulatory subunit is an enzyme that in humans is encoded by the GCLM gene. Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms.
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分子量
- 31 kDa
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基因ID
- 2730
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UniProt
- P48507
抗原
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