KDM6A 抗体 (AA 391-704)
Quick Overview for KDM6A 抗体 (AA 391-704) (ABIN7601589)
抗原
See all KDM6A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 391-704
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原理
- Anti-UTX/KDM6A Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-UTX/KDM6A Antibody Picoband® (ABIN7601589). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human UTX/KDM6A recombinant protein (Position: A391-A704).
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亚型
- IgG
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anti-Lysine (K)-Specific Demethylase 6A (KDM6A) (AA 641-740) antibody
KDM6A 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4E7 unconjugated
anti-Lysine (K)-Specific Demethylase 6A (KDM6A) (AA 1252-1401) antibodyKDM6A 适用: 人, 大鼠 WB, ELISA 宿主: 小鼠 Monoclonal 6E2D6 unconjugated
anti-Lysine (K)-Specific Demethylase 6A (KDM6A) (AA 1252-1401) antibodyKDM6A 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5C2A9 unconjugated
anti-Lysine (K)-Specific Demethylase 6A (KDM6A) (AA 620-749) antibodyKDM6A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 6A (KDM6A) (AA 1041-1074), (C-Term) antibodyKDM6A 适用: 小鼠 WB 宿主: 兔 Polyclonal RB52352 unconjugated
anti-Lysine (K)-Specific Demethylase 6A (KDM6A) (AA 797-832) antibodyKDM6A 适用: 人 WB 宿主: 兔 Polyclonal RB51279 unconjugated
anti-Lysine (K)-Specific Demethylase 6A (KDM6A) antibodyKDM6A 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 6A (KDM6A) (N-Term) antibodyKDM6A 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 6A (KDM6A) (C-Term) antibodyKDM6A 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 6A (KDM6A) (AA 1041-1074) antibodyKDM6A 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Agger, K., Cloos, P. A. C., Christensen, J., Pasini, D., Rose, S., Rappsilber, J., Issaeva, I., Canaani, E., Salcini, A. E., Helin, K. UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development. Nature 449: 731-734, 2007. 2. Chakraborty, A. A., Laukka, T., Myllykoski, M., Ringel, A. E., Booker, M. A., Tolstorukov, M. Y., Meng, Y. J., Meier, S. R., Jennings, R. B., Creech, A. L., Herbert, Z. T., McBrayer, S. K., Olenchock, B. A., Jaffe, J. D., Haigis, M. C., Beroukhim, R., Signoretti, S., Koivunen, P., Kaelin, W. G., Jr. Histone demethylase KDM6A ly senses oxygen to control chromatin and cell fate. Science 363: 1217-1222, 2019. 3. Faralli, H., Wang, C., Nakka, K., Benyoucef, A., Sebastian, S., Zhuang, L., Chu, A., Palii, C. G., Liu, C., Camellato, B., Brand, M., Ge, K., Dilworth, F. J. UTX demethylase activity is required for satellite cell-mediated muscle regeneration. J. Clin. Invest. 126: 1555-1565, 2016. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))
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别名
- KDM6A
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背景
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Synonyms: Hepatic leukemia factor, HLF
Tissue Specificity: Highly expressed in liver, lower levels in lung and kidney.
Background: Lysine-specific demethylase 6A also known as Ubiquitously transcribed tetratricopeptide repeat, X chromosome (UTX), is a protein which in humans is encoded by the KDM6A gene. This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3. Multiple alternatively spliced transcript variants have been found for this gene.
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分子量
- 154 kDa
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基因ID
- 7403
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UniProt
- O15550
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途径
- Tube Formation, Warburg Effect
抗原
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