MECR 抗体 (AA 39-359)
Quick Overview for MECR 抗体 (AA 39-359) (ABIN7601578)
抗原
See all MECR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 39-359
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原理
- Anti-MECR Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MECR Antibody Picoband® (ABIN7601578). Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MECR recombinant protein (Position: E39-A359).
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亚型
- IgG
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anti-Mitochondrial Trans-2-Enoyl-CoA Reductase (MECR) (AA 211-373) antibody
MECR 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Trans-2-Enoyl-CoA Reductase (MECR) antibodyMECR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Trans-2-Enoyl-CoA Reductase (MECR) (AA 1-373) antibodyMECR 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Trans-2-Enoyl-CoA Reductase (MECR) (C-Term) antibodyMECR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Trans-2-Enoyl-CoA Reductase (MECR) (AA 289-338) antibodyMECR 适用: 人, 小鼠, 大鼠, Cow, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Trans-2-Enoyl-CoA Reductase (MECR) (AA 1-373) antibodyMECR 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mitochondrial Trans-2-Enoyl-CoA Reductase (MECR) (AA 167-216) antibodyMECR 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 马, 兔, Bat, 猴, Hamster WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 1-2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Heimer, G., Keratar, J. M., Riley, L. G., Balasubramaniam, S., Eyal, E., Pietikainen, L. P., Hiltunen, J. K., Marek-Yagel, D., Hamada, J., Gregory, A., Rogers, C., Hogarth, P., and 24 others. MECR mutations cause childhood-onset dystonia and optic atrophy, a mitochondrial fatty acid synthesis disorder. Am. J. Hum. Genet. 99: 1229-1244, 2016. 2. Liu, Z., Shimura, M., Zhang, L., Zhang, W., Wang, J., Ogawa-Tominaga, M., Wang, J., Wang, X., Lv, J., Shi, W., Zhang, V. W., Murayama, K., Fang, F. Whole exome sequencing identifies a novel homozygous MECR mutation in a Chinese patient with childhood-onset dystonia and basal ganglia abnormalities, without optic atrophy. Mitochondrion 57: 222-229, 2021. 3. Miinalainen, I. J., Chen, Z.-J., Torkko, J. M., Pirila, P. L., Sormunen, R. T., Bergmann, U., Qin, Y.-M., Hiltunen, J. K. Characterization of 2-enoyl thioester reductase from mammals: an ortholog of Ybr026p/Mrf1'p of the yeast mitochondrial fatty acid synthesis type II. J. Biol. Chem. 278: 20154-20161, 2003. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MECR (Mitochondrial Trans-2-Enoyl-CoA Reductase (MECR))
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别名
- MECR
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背景
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Synonyms: Zinc finger protein 42 homolog, Zfp-42, Reduced expression protein 1, REX-1, hREX-1, Zinc finger protein 754, ZFP42, REX1, ZNF754
Tissue Specificity: Expressed in kidney, epidermal keratinocytes, prostate epithelial cells, bronchial and small airway lung epithelial cells (at protein level). Expressed in malignant kidney and several carcinoma cell lines (at protein level). Expressed in embryonic stem cells, kidney, epidermal keratinocytes, prostate epithelial cells, bronchial and small airway lung epithelial cells. Expressed in embryonal carcinomas, seminomas, malignant kidney and several carcinoma cell lines.
Background: Trans-2-enoyl-CoA reductase, mitochondrial is an enzyme that in humans is encoded by the MECR gene. The protein encoded by this gene is an oxidoreductase that catalyzes the last step in mitochondrial fatty acid synthesis. Defects in this gene are a cause of childhood-onset dystonia and optic atrophy.
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分子量
- 38 kDa
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基因ID
- 51102
抗原
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