FRK 抗体 (AA 39-339)
Quick Overview for FRK 抗体 (AA 39-339) (ABIN7601577)
抗原
See all FRK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 39-339
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原理
- Anti-FRK Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-FRK Antibody Picoband® (ABIN7601577). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human FRK recombinant protein (Position: Q39-A339).
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亚型
- IgG
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anti-Fyn-Related Kinase (FRK) (AA 2-300) antibody
FRK 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 1A8H2C12 unconjugated
anti-Fyn-Related Kinase (FRK) (AA 1-220) antibodyFRK 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fyn-Related Kinase (FRK) antibodyFRK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fyn-Related Kinase (FRK) (Internal Region) antibodyFRK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fyn-Related Kinase (FRK) (AA 234-491) antibodyFRK 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Fyn-Related Kinase (FRK) (AA 13-44), (N-Term) antibodyFRK 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB03106 unconjugated
anti-Fyn-Related Kinase (FRK) (Center) antibodyFRK 适用: 人, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Fyn-Related Kinase (FRK) (Middle Region) antibodyFRK 适用: 人, 小鼠, 大鼠, Pig, 犬, 豚鼠, Cow, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Fyn-Related Kinase (FRK) (AA 71-120) antibodyFRK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Fyn-Related Kinase (FRK) antibodyFRK 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Anneren, C., Reedquist, K. A., Bos, J. L., Welsh, M. GTK, a Src-related tyrosine kinase, induces nerve growth factor-independent neurite outgrowth in PC12 cells through activation of the Rap1 pathway: relationship to Shb tyrosine phosphorylation and elevated levels of focal adhesion kinase. J. Biol. Chem. 275: 29153-29161, 2000. 2. Cance, W. G., Craven, R. J., Bergman, M., Xu, L., Alitalo, K., Liu, E. T. Rak, a novel nuclear tyrosine kinase expressed in epithelial cells. Cell Growth Differ. 5: 1347-1355, 1994. 3. Cance, W. G., Craven, R. J., Weiner, T. M., Liu, E. T. Novel protein kinases expressed in human breast cancer. Int. J. Cancer 54: 571- -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- FRK (Fyn-Related Kinase (FRK))
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别名
- FRK
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背景
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Synonyms: Carbonic anhydrase 12, Carbonate dehydratase XII, Carbonic anhydrase XII, CA-XII, Tumor antigen HOM-RCC-3.1.3, CA12
Tissue Specificity: Highly expressed in colon, kidney, prostate, intestine and activated lymphocytes. Expressed at much higher levels in the renal cell cancers than in surrounding normal kidney tissue. Moderately expressed in pancreas, ovary and testis. Expressed in sweat glands and bronchiolar epithelium (PubMed:26911677).
Background: Fyn-related kinase (Frk) is a tyrosine kinase of the Src family. Also known as Rak, Gtk, and Iyk, Frk is predominantly expressed in epithelial tissues. Frk protein is 49 % and 47 % identical to Fyn and Csk, respectively. Src family kinases regulate an array of cellular processes, including growth factor signaling, cytoskeleton dynamics, and cell proliferation.
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分子量
- 58 kDa
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基因ID
- 2444
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UniProt
- P42685
抗原
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