Myosin VI 抗体 (AA 383-786)
Quick Overview for Myosin VI 抗体 (AA 383-786) (ABIN7601557)
抗原
See all Myosin VI (MYO6) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 383-786
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原理
- Anti-MYO6 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MYO6 Antibody Picoband® (ABIN7601557). Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MYO6 recombinant protein (Position: Q383-H786).
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亚型
- IgG
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anti-Myosin VI (MYO6) (N-Term) antibody
MYO6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Myosin VI (MYO6) (AA 1188-1285) antibodyMYO6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E12 unconjugated
anti-Myosin VI (MYO6) (AA 1166-1195), (C-Term) antibodyMYO6 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB19127 unconjugated
anti-Myosin VI (MYO6) (AA 1173-1203), (C-Term) antibodyMYO6 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Myosin VI (MYO6) (N-Term) antibodyMYO6 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myosin VI (MYO6) (AA 1016-1285) antibodyMYO6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Ahituv, N., Sobe, T., Robertson, N. G., Morton, C. C., Taggart, R. T., Avraham, K. B. Genomic structure of the human unconventional myosin VI gene. Gene 261: 269-275, 2000. 2. Ahmed, Z. M., Morell, R. J., Riazuddin, S., Gropman, A., Shaukat, S., Ahmad, M. M., Mohiddin, S. A., Fananapazir, L., Caruso, R. C., Husnain, T., Khan, S. N., Riazuddin, S., Griffith, A. J., Friedman, T. B., Wilcox, E. R. Mutations of MYO6 are associated with recessive deafness, DFNB37. Am. J. Hum. Genet. 72: 1315-1322, 2003. 3. Altman, D., Sweeney, H. L., Spudich, J. A. The mechanism of myosin VI translocation and its load-induced anchoring. Cell 116: 737-749, 2004. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Myosin VI (MYO6)
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别名
- MYO6
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背景
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Synonyms: Homeobox protein SIX3,Sine oculis homeobox homolog 3,SIX3,
Tissue Specificity: Highly expressed in placenta, lung, kidney, testis and ovary. Weakly expressed in spleen and thymus. Not expressed in peripheral blood lymphocytes. Detected in hippocampus.
Background: Unconventional myosin-VI, is a protein that in humans is coded for by MYO6. This gene encodes a reverse-ion motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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分子量
- 150 kDa
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基因ID
- 4646
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途径
- Sensory Perception of Sound, Dicarboxylic Acid Transport, Asymmetric Protein Localization
抗原
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