Tryptophan Hydroxylase 1 抗体 (AA 383-444)
Quick Overview for Tryptophan Hydroxylase 1 抗体 (AA 383-444) (ABIN7601556)
抗原
See all Tryptophan Hydroxylase 1 (TPH1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 383-444
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原理
- Anti-Tryptophan Hydroxylase/TPH1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Tryptophan Hydroxylase/TPH1 Antibody Picoband® (ABIN7601556). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Tryptophan Hydroxylase/TPH1 recombinant protein (Position: K383-I444).
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亚型
- IgG
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anti-Tryptophan Hydroxylase 1 (TPH1) (AA 35-62), (N-Term) antibody
TPH1 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB21510 unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) (AA 257-405) antibodyTPH1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) (pSer58) antibodyTPH1 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) (AA 345-444) antibodyTPH1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) (N-Term) antibodyTPH1 适用: 人, 小鼠, 大鼠, 兔, 小鸡 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) (AA 26-75) antibodyTPH1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) (AA 231-280) antibodyTPH1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) antibodyTPH1 适用: 人 WB, IHC, IF/ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) (pSer260) antibodyTPH1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) (pSer58) antibodyTPH1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. "Entrez Gene: TPH1 tryptophan hydroxylase 1 (tryptophan 5-monooxygenase)". 2. New AS, Gelernter J, Yovell Y, Trestman RL, Nielsen DA, Silverman J, Mitropoulou V, Siever LJ (1998). "Tryptophan hydroxylase genotype is associated with impulsive-aggression measures: a preliminary study". Am. J. Med. Genet. 81 (1): 13-7. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Tryptophan Hydroxylase 1 (TPH1)
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别名
- TPH1
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背景
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Synonyms: Tryptophan 5-hydroxylase 1, Tryptophan 5-monooxygenase 1, TPH1, TPH, TPRH, TRPH
Tissue Specificity: Isoform 2 seems to be less widely expressed than isoform 1.
Background: Tryptophan hydroxylase 1 (TPH1) is an isoenzyme of tryptophan hydroxylase which in humans is encoded by the TPH1 gene. This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.
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分子量
- 60 kDa
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基因ID
- 7166
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UniProt
- P17752
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途径
- Feeding Behaviour
抗原
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