MNT 抗体 (AA 381-564)
Quick Overview for MNT 抗体 (AA 381-564) (ABIN7601555)
抗原
See all MNT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 381-564
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原理
- Anti-MNT Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MNT Antibody Picoband® (ABIN7601555). Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MNT recombinant protein (Position: H381-N564).
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亚型
- IgG
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anti-MNT, MAX Dimerization Protein (MNT) (Internal Region) antibody
MNT 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-MNT, MAX Dimerization Protein (MNT) (Internal Region) antibodyMNT 适用: 人 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-MNT, MAX Dimerization Protein (MNT) (N-Term) antibodyMNT 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 马, Pig, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
anti-MNT, MAX Dimerization Protein (MNT) (AA 473-582) antibodyMNT 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-MNT, MAX Dimerization Protein (MNT) (N-Term) antibodyMNT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-MNT, MAX Dimerization Protein (MNT) (Internal Region) antibodyMNT 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hurlin, P. J., Queva, C., Eisenman, R. N. Mnt, a novel Max-interacting protein is coexpressed with Myc in proliferating cells and mediates repression at Myc binding sites. Genes Dev. 11: 44-58, 1997. 2. Lo Nigro, C., Venesio, T., Reymond, A., Meroni, G., Alberici, P., Cainarca, S., Enrico, F., Stack, M., Ledbetter, D. H., Liscia, D. S., Ballabio, A., Carrozzo, R. The human ROX gene: genomic structure and mutation analysis in human breast tumors. Genomics 49: 275-282, 1998. 3. Meroni, G., Reymond, A., Alcalay, M., Borsani, G., Tanigami, A., Tonlorenzi, R., Lo Nigro, C., Messali, S., Zollo, M., Ledbetter, D. H., Brent, R., Ballabio, A., Carrozzo, R. Rox, a novel bHLHZip protein expressed in quiescent cells that heterodimerizes with Max, binds a non-canonical E box and acts as a transcriptional repressor. EMBO J. 16: 2892-2906, 1997. Note: Erratum: EMBO J. 16: 6055 only, 1997. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MNT (MNT, MAX Dimerization Protein (MNT))
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别名
- MNT
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背景
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Synonyms: Max-binding protein MNT, Class D basic helix-loop-helix protein 3, bHLHd3, Myc antagonist MNT, Protein ROX, MNT, BHLHD3, ROX
Tissue Specificity: Expressed in some normal epithelial tissues and in some carcinoma cell lines.
Background: MNT (Max's Next Tango) is a Max-binding protein that is encoded by the MNT gene. It is mapped to 17p13.3. The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.
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分子量
- 62 kDa
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基因ID
- 4335
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UniProt
- Q99583
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途径
- Chromatin Binding, Regulation of Muscle Cell Differentiation
抗原
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