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Chromogranin A 抗体 (AA 378-425)

This anti-Chromogranin A antibody is a 兔 多克隆 antibody detecting Chromogranin A in IHC, FACS, WB 和 ELISA. Suitable for 大鼠 和 小鼠.
产品编号 ABIN7601533
发货至: 中国

Quick Overview for Chromogranin A 抗体 (AA 378-425) (ABIN7601533)

抗原

See all Chromogranin A (CHGA) 抗体
Chromogranin A (CHGA)

适用

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大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This Chromogranin A antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Flow Cytometry (FACS), Western Blotting (WB), ELISA
  • 抗原表位

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    AA 378-425

    原理

    Anti-Chromogranin A/Chga Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Chromogranin A/Chga Antibody Picoband® (ABIN7601533). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived mouse Chga recombinant protein (Position: D378-K425).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Mouse
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse
    ELISA, 0.1-0.5 μg/mL, -
    1. Helman LJ, Ahn TG, Levine MA, Allison A, Cohen PS, Cooper MJ, Cohn DV, Israel MA (August 1988). "Molecular cloning and primary structure of human chromogranin A (secretory protein I) cDNA". J. Biol. Chem. 263 (23): 11559-63. 2. Cotesta D, Caliumi C, Al111 P, Petramala L, Reale MG, Masciangelo R, Signore A, Cianci R, D'Erasmo E, Letizia C (2005). "High plasma levels of human chromogranin A and adrenomedullin in patients with pheochromocytoma". Tumori 91 (1): 53-8.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    Chromogranin A (CHGA)

    别名

    Chga

    背景

    Synonyms: Kit ligand, Mast cell growth factor, MGF, Stem cell factor, SCF, c-Kit ligand, Soluble KIT ligand, sKITLG, KITLG, MGF, SCF,

    Background: CHGA, also known as CGA or chromogranin A, is an acidic protein costored and coreleased with catecholamines from storage granules in the adrenal medulla. CHGA is a member of the granin family of neuroendocrine secretory protein, It is located in secretory vesicles of neurons and endocrine cells. In humans, CHGA protein is encoded by the CHGA gene, and it is mapped to 14q32.12. CHGA gene product is a precursor to three biologically active peptides: vasostatin, pancreastatin, and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine).

    分子量

    80 kDa

    基因ID

    12652

    UniProt

    P26339

    途径

    Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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