PI4KB 抗体 (AA 375-671)
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北京 101111
Quick Overview for PI4KB 抗体 (AA 375-671) (ABIN7601530)
抗原
See all PI4KB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 375-671
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原理
- Anti-PI4KB Antibody
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交叉反应 （详细）
- No cross reactivity with other proteins.
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预测反应
- Human PI4KB shares 100%,99.7% amino acid (aa) sequence identity with mouse,rat PI4KB,respectively
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产品特性
- Anti-PI4KB Antibody. Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PI4KB recombinant protein (Position: D375-D671). Human PI4KB shares 100% and 99.7% amino acid (aa) sequence identity with mouse and rat PI4KB, respectively
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亚型
- IgG
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anti-Phosphatidylinositol 4-Kinase, Catalytic, beta (PI4KB) (AA 20-51), (N-Term) antibody
PI4KB 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1676 unconjugated
anti-Phosphatidylinositol 4-Kinase, Catalytic, beta (PI4KB) (AA 519-548) antibodyPI4KB 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18563 unconjugated
anti-Phosphatidylinositol 4-Kinase, Catalytic, beta (PI4KB) (AA 731-828) antibodyPI4KB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B1 unconjugated
anti-Phosphatidylinositol 4-Kinase, Catalytic, beta (PI4KB) (Middle Region) antibodyPI4KB 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol 4-Kinase, Catalytic, beta (PI4KB) (N-Term) antibodyPI4KB 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol 4-Kinase, Catalytic, beta (PI4KB) (Internal Region) antibodyPI4KB 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol 4-Kinase, Catalytic, beta (PI4KB) (AA 755-804) antibodyPI4KB 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, 兔, Cow, 豚鼠, 马, 非洲爪蟾, Bat, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol 4-Kinase, Catalytic, beta (PI4KB) (AA 251-300) antibodyPI4KB 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, 兔, Cow, 豚鼠, 马, 非洲爪蟾, Bat, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol 4-Kinase, Catalytic, beta (PI4KB) (Middle Region) antibodyPI4KB 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, 兔, Cow, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- PI4KB (Phosphatidylinositol 4-Kinase, Catalytic, beta (PI4KB))
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别名
- PI4KB
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背景
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Background: Phosphatidylinositol 4-kinase beta is an enzyme that in humans is encoded by the PI4KB gene. Inositol phospholipids have an important role in intracellular signaling in response to hormones, growth factors and neurotransmitters. Phosphatidylinositol 4-kinase phosphorylates phosphatidylinositol (PI) to phosphatidylinositol-4-phosphate (PIP). In a second step, PIP is further phosphorylated to phosphatidylinositol-4,5-bisphosphate (PIP2), and PIP2 is subsequently hydrolyzed by phospholipase C, producing the two intracellular second messengers, inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PI4K230, PI4K92 and PI4K55 are three PI4 kinase isoforms that have been characterized and classified according to their molecular weights of 230, 92 and 55 kD. Previously, PI4 kinases were classified into type II and III enzymes. All isoforms are located on distinct membranes and cellular compartments suggesting various tasks. PI4K230 is located at the endoplasmatic reticulum and outer membranes of mitochondria, PI4K92 at the Golgi apparatus and endoplasmatic reticulum, and PI4K55 at the plasma membrane and endosomes. PI4K230 is predominantly expressed in brain and moderately sensitive to wortmannin as well as specifically and irreversibly inhibited by cyclitol derivatives.
Gene Full Name: phosphatidylinositol 4-kinase beta
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分子量
- 95 kDa
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基因ID
- 5298
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UniProt
- Q9UBF8
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途径
- Inositol Metabolic Process
抗原
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