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HGD 抗体 (AA 374-445)

This anti-HGD antibody is a 小鼠 单克隆 antibody detecting HGD in WB, IHC 和 FACS. Suitable for 人.
产品编号 ABIN7601528
发货至: 中国

Quick Overview for HGD 抗体 (AA 374-445) (ABIN7601528)

抗原

See all HGD 抗体
HGD (Homogentisate 1,2-Dioxygenase (HGD))

适用

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宿主

  • 53
  • 5
小鼠

克隆类型

  • 52
  • 6
单克隆

标记

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This HGD antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

克隆位点

2F11E1
  • 抗原表位

    • 15
    • 5
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    AA 374-445

    原理

    Anti-HGD Antibody Picoband® (monoclonal, 2F11E1)

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-HGD Antibody Picoband® (monoclonal, 2F11E1) (ABIN7601528). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human HGD recombinant protein (Position: D374-N445).

    亚型

    IgG2b
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    1. Fernandez-Canon, J. M., Granadino, B., Beltran-Valero de Bernabe, D., Renedo, M., Fernandez-Ruiz, E., Penalva, M. A., Rodriguez de Cordoba, S. The molecular basis of alkaptonuria. Nature Genet. 14: 19-24, 1996. 2. Vilboux, T., Kayser, M., Introne, W., Suwannarat, P., Bernardini, I., Fischer, R., O'Brien, K., Kleta, R., Huizing, M., Gahl, W. A. Mutation spectrum of homogentisic acid oxidase (HGD) in alkaptonuria. Hum. Mutat. 30: 1611-1619, 2009.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    HGD (Homogentisate 1,2-Dioxygenase (HGD))

    别名

    HGD

    背景

    Synonyms: Ras-related protein Rab-5A, RAB5A, RAB5

    Tissue Specificity: Widely expressed in fetal and adult tissues.

    Background: The HGD gene encodes homogentisate 1,2-dioxygenase (HGD), an enzyme involved in the catabolism of phenylalanine and tyrosine. This enzyme is involved in the catabolism of the amino acids tyrosine and phenylalanine. Mutations in this gene are the cause of the autosomal recessive metabolism disorder alkaptonuria. This gene is mapped to chromosome 3q21-q23 by a preliminary PCR screen of hamster/human somatic cell hybrid genomic DNA samples and by fluorescence in situ hybridization.

    分子量

    50 kDa

    基因ID

    3081

    UniProt

    Q93099
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