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KIF5A 抗体 (AA 374-1032)

This anti-KIF5A antibody is a 兔 多克隆 antibody detecting KIF5A in WB, ELISA 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7601527
发货至: 中国

Quick Overview for KIF5A 抗体 (AA 374-1032) (ABIN7601527)

抗原

See all KIF5A 抗体
KIF5A (Kinesin Family Member 5A (KIF5A))

适用

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  • 10
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  • 1
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人, 小鼠, 大鼠

宿主

  • 29
  • 9
  • 1

克隆类型

  • 30
  • 9
多克隆

标记

  • 32
  • 4
  • 3
This KIF5A antibody is un-conjugated

应用范围

  • 38
  • 28
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  • 9
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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

    • 5
    • 5
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 374-1032

    原理

    Anti-KIF5A Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-KIF5A Antibody Picoband® (ABIN7601527). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human KIF5A recombinant protein (Position: E374-S1032).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Blair, M. A., Ma, S., Hedera, P. Mutation in KIF5A can also cause adult-onset hereditary spastic paraplegia. Neurogenetics 7: 47-50, 2006. 2. Brenner, D., Yilmaz, R., Muller, K., Grehl, T., Petri, S., Meyer, T., Grosskreutz, J., Weydt, P., Ruf, W., Neuwirth, C., Weber, M., Pinto, S., and 29 others. Hot-spot KIF5A mutations cause familial ALS. Brain 141: 688-697, 2018. 3. Crimella, C., Baschirotto, C., Arnoldi, A., Tonelli, A., Tenderini, E., Airoldi, G., Martinuzzi, A., Trabacca, A., Losito, L., Scarlato, M., Benedetti, S., Scarpini, E., Spinicci, G., Bresolin, N., Bassi, M. T. Mutations in the motor and stalk domains of KIF5A in spastic paraplegia type 10 and in axonal Charcot-Marie-Tooth type 2. Clin. Genet. 82: 157-164, 2012.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    KIF5A (Kinesin Family Member 5A (KIF5A))

    别名

    KIF5A

    背景

    Synonyms: Protein ERGIC-53, ER-Golgi intermediate compartment 53 kDa protein, Gp58, Intracellular mannose-specific lectin MR60, Lectin mannose-binding 1, LMAN1, ERGIC53, F5F8D

    Tissue Specificity: Ubiquitous.

    Background: Kinesin heavy chain isoform 5A is a protein that in humans is encoded by the KIF5A gene. This gene encodes a member of the kinesin family of proteins. Members of this family are part of a multisubunit complex that functions as a microtubule motor in intracellular organelle transport. Mutations in this gene cause autosomal dominant spastic paraplegia 10.

    分子量

    117 kDa

    基因ID

    3798

    UniProt

    Q12840
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