AASS 抗体 (AA 37-865)
Quick Overview for AASS 抗体 (AA 37-865) (ABIN7601519)
抗原
See all AASS 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 37-865
-
原理
- Anti-AASS Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-AASS Antibody Picoband® (ABIN7601519). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human AASS recombinant protein (Position: E37-N865).
-
亚型
- IgG
-
-
anti-Aminoadipate Semialdehyde Synthase (AASS) (AA 33-455) antibody
AASS 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aminoadipate Semialdehyde Synthase (AASS) (AA 224-364) antibodyAASS 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aminoadipate Semialdehyde Synthase (AASS) (C-Term) antibodyAASS 适用: 人, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Aminoadipate Semialdehyde Synthase (AASS) (AA 477-926) antibodyAASS 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aminoadipate Semialdehyde Synthase (AASS) (AA 264-294) antibodyAASS 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB14893 unconjugated
anti-Aminoadipate Semialdehyde Synthase (AASS) (AA 805-834), (C-Term) antibodyAASS 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB14895 unconjugated
anti-Aminoadipate Semialdehyde Synthase (AASS) (AA 812-841), (C-Term) antibodyAASS 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
anti-Aminoadipate Semialdehyde Synthase (AASS) (Internal Region) antibodyAASS 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Dancis, J., Hutzler, J., Woody, N. C., Cox, R. P. Multiple enzyme defects in familial hyperlysinemia. Pediat. Res. 10: 686-691, 1976. 2. Houten, S. M., te Brinke, H., Denis, S., Ruiter, J. P. N., Knegt, A. C., de Klerk, J. B. C., Augoustides-Savvopoulou, P., Haberle, J., Baumgartner, M. R., Coskun, T., Zschocke, J., Sass, J. O., Poll-The, B. T., Wanders, R. J. A., Duran, M. Genetic basis of hyperlysinemia. Orphanet J. Rare Dis. 8: 57, 2013. Note: Electronic Article. 3. Sacksteder, K. A., Biery, B. J., Morrell, J. C., Goodman, B. K., Geisbrecht, B. V., Cox, R. P., Gould, S. J., Geraghty, M. T. Identification of the alpha-aminoadipic semialdehyde synthase gene, which is defective in familial hyperlysinemia. Am. J. Hum. Genet. 66: 1736-1743, 2000. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- AASS (Aminoadipate Semialdehyde Synthase (AASS))
-
别名
- AASS
-
背景
-
Synonyms: Mesoderm posterior protein 1, Class C basic helix-loop-helix protein 5, bHLHc5, MESP1, BHLHC5
Tissue Specificity: Highly expressed in brain and weakly in heart, small intestine and uterus. Isoform 1A is mostly expressed in granular cell and molecular layer. Isoform 1B is mostly expressed in Purkinje cells. Isoform 1E is predominantly expressed in peripheral tissues as kidney, lung, trachea, colon, small intestine, stomach, bone marrow, thymus and mammary gland. .
Background: Alpha-aminoadipic semialdehyde synthase is an enzyme encoded by the AASS gene in humans and is involved in their major lysine degradation pathway. This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia.
-
分子量
- 102 kDa
-
基因ID
- 10157
-
途径
- SARS-CoV-2 Protein Interactome
抗原
-
