SAMHD1 抗体 (AA 37-626)
Quick Overview for SAMHD1 抗体 (AA 37-626) (ABIN7601516)
抗原
See all SAMHD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 37-626
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原理
- Anti-SAMHD1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SAMHD1 Antibody Picoband® (ABIN7601516). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SAMHD1 recombinant protein (Position: E37-M626).
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亚型
- IgG
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anti-SAM Domain and HD Domain 1 (SAMHD1) antibody
SAMHD1 适用: 人, 小鼠, 大鼠, 猴, 犬 WB, IF, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1A1 unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) antibodySAMHD1 适用: 人, 猴 WB, IF, FACS 宿主: 小鼠 Monoclonal 1F6 unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) (AA 1-626) antibodySAMHD1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) (AA 387-626) antibodySAMHD1 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) (AA 1-314) antibodySAMHD1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) (Internal Region) antibodySAMHD1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) (AA 1-626) antibodySAMHD1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) (AA 256-370) antibodySAMHD1 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) (AA 426-657) antibodySAMHD1 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) (AA 288-337) antibodySAMHD1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Behrendt, R., Schumann, T., Gerbaulet, A., Nguyen, L. A., Schubert, N., Alexopoulos, D., Berka, U., Lienenklaus, S., Peschke, K., Gibbert, K., Wittmann, S., Lindemann, D., Weiss, S., Dahl, A., Naumann, R., Dittmer, U., Kim, B., Mueller, W., Gramberg, T., Roers, A. Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral response. Cell Rep. 4: 689-696, 2013. 2. Coquel, F., Silva, M.-J., Techer, H., Zadorozhny, K., Sharma, S., Nieminuszczy, J., Mettling, C., Dardillac, E., Barthe, A., Schmitz, A.-L., Promonet, A., Cribier, A., and 9 others. SAMHD1 acts at stalled replication forks to prevent interferon induction. Nature 557: 57-61, 2018. 3. Crow, Y. J., Chase, D. S., Lowenstein Schmidt, J., Szynkiewicz, M., Forte, G. M. A., Gornall, H. L., Oojageer, A., Anderson, B., Pizzino, A., Helman, G., Abdel-Hamid, M. S., Abdel-Salam, G. M., and 124 others. Characterization of human disease phenotypes associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR, and IFIH1. Am. J. Med. Genet. 167A: 296-312, 2015. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))
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别名
- SAMHD1
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背景
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Synonyms: Vesicle-fusing ATPase, N-ethylmaleimide-sensitive fusion protein, NEM-sensitive fusion protein, Vesicular-fusion protein NSF, NSF
Background: SAM domain and HD domain-containing protein 1 is a protein that in humans is encoded by the SAMHD1 gene. This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome.
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分子量
- 72 kDa
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基因ID
- 25939
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UniProt
- Q9Y3Z3
抗原
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