SAMHD1 抗体 (AA 37-626)
Quick Overview for SAMHD1 抗体 (AA 37-626) (ABIN7601514)
抗原
See all SAMHD1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 37-626
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原理
- Anti-SAMHD1 Antibody Picoband® (monoclonal, 10H8)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SAMHD1 Antibody Picoband® (monoclonal, 10H8) (ABIN7601514). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SAMHD1 recombinant protein (Position: E37-M626).
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亚型
- IgG2b
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anti-SAM Domain and HD Domain 1 (SAMHD1) antibody
SAMHD1 适用: 人, 小鼠, 大鼠, 猴, 犬 WB, IF, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1A1 unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) antibodySAMHD1 适用: 人, 猴 WB, IF, FACS 宿主: 小鼠 Monoclonal 1F6 unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) (AA 1-626) antibodySAMHD1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) (AA 387-626) antibodySAMHD1 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) (AA 1-314) antibodySAMHD1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) (Internal Region) antibodySAMHD1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) (AA 1-626) antibodySAMHD1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) (AA 256-370) antibodySAMHD1 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) (AA 426-657) antibodySAMHD1 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) (AA 288-337) antibodySAMHD1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Behrendt, R., Schumann, T., Gerbaulet, A., Nguyen, L. A., Schubert, N., Alexopoulos, D., Berka, U., Lienenklaus, S., Peschke, K., Gibbert, K., Wittmann, S., Lindemann, D., Weiss, S., Dahl, A., Naumann, R., Dittmer, U., Kim, B., Mueller, W., Gramberg, T., Roers, A. Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral response. Cell Rep. 4: 689-696, 2013. 2. Coquel, F., Silva, M.-J., Techer, H., Zadorozhny, K., Sharma, S., Nieminuszczy, J., Mettling, C., Dardillac, E., Barthe, A., Schmitz, A.-L., Promonet, A., Cribier, A., and 9 others. SAMHD1 acts at stalled replication forks to prevent interferon induction. Nature 557: 57-61, 2018. 3. Crow, Y. J., Chase, D. S., Lowenstein Schmidt, J., Szynkiewicz, M., Forte, G. M. A., Gornall, H. L., Oojageer, A., Anderson, B., Pizzino, A., Helman, G., Abdel-Hamid, M. S., Abdel-Salam, G. M., and 124 others. Characterization of human disease phenotypes associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR, and IFIH1. Am. J. Med. Genet. 167A: 296-312, 2015. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))
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别名
- SAMHD1
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背景
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Synonyms: RNA-binding protein EWS, EWS oncogene, Ewing sarcoma breakpoint region 1 protein, EWSR1, EWS
Tissue Specificity: Ubiquitous.
Background: SAM domain and HD domain-containing protein 1 is a protein that in humans is encoded by the SAMHD1 gene. This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome.
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分子量
- 72 kDa
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基因ID
- 25939
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UniProt
- Q9Y3Z3
抗原
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