ATIC 抗体 (AA 37-592)
Quick Overview for ATIC 抗体 (AA 37-592) (ABIN7601511)
抗原
See all ATIC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 37-592
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原理
- Anti-ATIC Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-ATIC Antibody Picoband® (ABIN7601511). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ATIC recombinant protein (Position: T37-H592).
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亚型
- IgG
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anti-5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) (AA 301-592) antibody
ATIC 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) (C-Term) antibodyATIC 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) antibodyATIC 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) antibodyATIC 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, FACS 宿主: 小鼠 Monoclonal 1D2 unconjugated
anti-5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) (Middle Region) antibodyATIC 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) antibodyATIC 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) (AA 1-592) antibodyATIC 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) (AA 1-592) antibodyATIC 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) (AA 379-428) antibodyATIC 适用: 人, 小鼠, 大鼠, 犬, 兔, 马, Cow, 豚鼠, Pig, Hamster, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) antibodyATIC 适用: 人, 小鼠, 大鼠, 犬, 猴 WB 宿主: 小鼠 Monoclonal 2C10 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Baresova, V., Skopova, V., Sikora, J., Patterson, D., Sovova, J., Zikanova, M., Kmoch, S. Mutations of ATIC and ADSL affect purinosome assembly in cultured skin fibroblasts from patients with AICA-ribosiduria and ADSL deficiency. Hum. Molec. Genet. 21: 1534-1543, 2012. 2. Greasley, S. E., Horton, P., Ramcharan, J., Beardsley, G. P., Benkovic, S. J., Wilson, I. A. Crystal structure of a bifunctional transformylase and cyclohydrolase enzyme in purine biosynthesis. Nature Struct. Biol. 8: 402-406, 2001. 3. Marie, S., Heron, B., Bitoun, P., Timmerman, T., Van den Berghe, G., Vincent, M.-F. AICA-ribosiduria: a novel, neurologically devastating inborn error of purine biosynthesis caused by mutation of ATIC. Am. J. Hum. Genet. 74: 1276-1281, 2004. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- ATIC (5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC))
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别名
- ATIC
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背景
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Synonyms: POU domain, class 4, transcription factor 1
Tissue Specificity: Expressed in the brain and the retina. Present in the developing brain, spinal cord and eye.
Background: Bifunctional purine biosynthesis protein PURH is a protein that in humans is encoded by the ATIC gene. This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.
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分子量
- 65 kDa
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基因ID
- 471
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UniProt
- P31939
抗原
-
